Baccharis anomala DC. extract reduces inflammation and attenuates hepatic fibrosis in vivo by decreasing NF-kB and extracellular matrix compounds

de Souza Basso, Bruno; Bastos, Matheus Scherer; Antunes, Géssica Luana; Matzenbacher, Lucas Strassburger; Rodrigues, Kétlin Fernanda; Garcia, Maria Claudia Rosa; de Sousa, Arieli Cruz; Levorse, Vitor Giancarlo; Luft, Carolina; Tonial, Giovana Vivan; Pavanato, Giovanna Mezzomo; Astarita, Leandro Vieira; da Silva Melo, Denizar Alberto; Donadio, Márcio Vinícius Fagundes; Santarém, Eliane Romanato; de Oliveira, Jarbas Rodrigues

doi:10.1016/j.toxicon.2023.107560

Toxicon

2024

DOI: 10.1016/j.toxicon.2023.107560

|View full text |Cite

Baccharis anomala DC. extract reduces inflammation and attenuates hepatic fibrosis in vivo by decreasing NF-kB and extracellular matrix compounds

Bruno de Souza Basso,

Matheus Scherer Bastos,

Géssica Luana Antunes

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2025

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Research Progress on Natural Products Alleviating Liver Inflammation and Fibrosis via NF‐κB Pathway

Li,

2025

Chemistry & Biodiversity

View full text Add to dashboard Cite

Liver fibrosis is a key pathological process in chronic liver diseases, regulated by various cytokines and signaling pathways. Among these, the NF‐κB signaling pathway plays a significant role in the initiation and progression of liver fibrosis. Recently, natural products have garnered attention as potential anti‐fibrotic agents. This review highlights recent studies on how natural products, including flavonoids, terpenoids, polysaccharides, phenols, alkaloids, quinones, phenylpropanoids, steroids, and nitrogen compounds, mitigate liver fibrosis by modulating the NF‐κB signaling pathway. Specifically, it examines how these natural products influence NF‐κB activation, nuclear translocation, and downstream signaling, thereby inhibiting inflammatory responses, reducing apoptosis, and regulating hepatic stellate cell (HSC) activity, ultimately achieving therapeutic effects against liver fibrosis. A deeper understanding of the mechanisms by which natural products regulate the NF‐κB signaling pathway can provide crucial theoretical foundations and valuable insights for the development of novel anti‐fibrotic drugs.

show abstract

Research Progress on Natural Products Alleviating Liver Inflammation and Fibrosis via NF‐κB Pathway

Li,

2025

Chemistry & Biodiversity

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Baccharis anomala DC. extract reduces inflammation and attenuates hepatic fibrosis in vivo by decreasing NF-kB and extracellular matrix compounds

Cited by 1 publication

References 26 publications

Research Progress on Natural Products Alleviating Liver Inflammation and Fibrosis via NF‐κB Pathway

Research Progress on Natural Products Alleviating Liver Inflammation and Fibrosis via NF‐κB Pathway

Contact Info

Product

Resources

About