Back to basics

Huang, Glen; Stewardson, Andrew J.; Grayson, M. Lindsay

doi:10.1097/qco.0000000000000080

Cited by 32 publications

(16 citation statements)

References 92 publications

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“…Staff should receive education on the importance of PHH in the prevention of hospital-acquired infection; and staff need to be instructed to provide verbal PHH education to all newly admitted patients, and to provide reminders, assistance and encouragement for PHH practice 16 17. In addition, it is also important to ensure that HH products—such as alcohol-based hand wipes or ABHR—are accessible to patients who are bedridden and are unable to get to the sink 18 19. Staff or family members should be instructed to provide assistance to improve PHH opportunities 18…”

Section: Discussionmentioning

confidence: 99%

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Knowledge and practice of hand hygiene among hospitalised patients in a tertiary general hospital in China and their attitudes: a cross-sectional survey

Yao-hong

Zeng

et al. 2019

BMJ Open

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ObjectivesWe aimed to gain a better understanding of patients’ practice of hand hygiene (HH) and their knowledge and attitudes.DesignA cross-sectional survey.SettingA 3500-bed university-affiliated medical hospital in China.ParticipantsInpatients and their family members or caregivers.MethodsAn anonymous, self-reported questionnaire were used to collect data.ResultsA total of 376 questionnaires were issued, and 310 respondents completed it. Of the 310 respondents, 47.4% had received HH education, and 13.5% had a completing understanding of HH. A majority of patients believed that handwashing was important for disease recovery, and that it could prevent infection development. A total of 62.3% of patients washed their hands <5 times a day and 49.0% spent <1 min every time. With regards to the seven steps of handwashing, 96.45% of the respondents adhered to the first step (washing the palms), but only 20.6% adhered to the fifth step (thumbs) and 17.7% to the sixth step (fingertips). Most respondents washed their hands only when visibly dirty. Few patients washed their hands before drinking fluids, and before and after interacting with visitors. HH compliance was lower among intensive care unit patients than medical patients.ConclusionsIn conclusion, this study demonstrated that patients had a positive attitude towards HH. However, their levels of knowledge and practice were unsatisfactory. A systematical education about patientHH is needed in future to correct this knowledge and behaviour.

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Section: Discussionmentioning

confidence: 99%

“…In addition, it is also important to ensure that HH products—such as alcohol-based hand wipes or ABHR—are accessible to patients who are bedridden and are unable to get to the sink 18 19. Staff or family members should be instructed to provide assistance to improve PHH opportunities 18…”

Section: Discussionmentioning

confidence: 99%

Knowledge and practice of hand hygiene among hospitalised patients in a tertiary general hospital in China and their attitudes: a cross-sectional survey

Yao-hong

Zeng

et al. 2019

BMJ Open

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“…In order to minimize the risk of acquiring an opportunistic infection, patients benefit from strict compliance with infection prevention and control 38 . More efforts should be invested in creating better awareness for this issue amongst medical personal.…”

Section: Discussionmentioning

confidence: 99%

“…organ transplantation post-op, could have beneficial effects. Although a recent review showed that noncompliance resulted in a paradoxical increase in adverse events 38 .…”

Section: Discussionmentioning

confidence: 99%

Early immune anergy towards recall antigens and mitogens in patients at onset of septic shock

Feuerecker¹,

Sudhoff²,

Crucian

et al. 2018

Sci Rep

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The pathology of sepsis is typically characterized by an infection and excessive initial inflammation including a cytokine storm, followed by a state of immune suppression or paralysis. This classical view of a two peak kinetic immune response is currently controversially discussed. This study was a sub-study of the randomized clinical Trial SISPCT registered with www.clinicaltrials.gov (NCT00832039, Registration date: 29/01/2009). Blood samples from 76 patients with severe sepsis and septic shock were incubated for 48 h at 37 °C in vitro with bacterial or fungal recall-antigens or specific mitogen antigens within 24 hours of sepsis onset. Recall-antigen stimulation led to a severe dampening of normal cytokine release. This immunologic anergy was similarly observed after mitogen stimulation. Moreover, patients under hydrocortisone therapy or with lowered arterial oxygen tension had further reductions in cytokine levels upon B- and T-cell mitogen stimulation. This investigation reveals an early onset of immunoparalysis during sepsis. This immune incompetence in mounting an adequate response to further infections includes previously sensitized pathogens, as seen with recall-antigens. Also, the immune-suppressive role of hydrocortisone and low PaO2 is highlighted. Aside from early broad-spectrum antimicrobial therapy, our findings reinforce the need for maximal immunological support and protection against further infections at the onset of sepsis.

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“…The long-term survival of these bacteria in the environment increases their chance of transmission to sensitive hosts via the ingestion of such contaminated products, food and water, or through their contact with such inanimate objects [ 6 , 10 , 17 , 37 ]. Furthermore, farm personnel also play a role in transmission of bacteria within and among the farms through their contact with contaminated hands, clothes and boots [ 4 , 16 , 18 , 36 ].…”

mentioning

confidence: 99%

Inactivation of bacteria on surfaces by sprayed slightly acidic hypochlorous acid water: <i>in vitro</i> experiments

Hakim

Alam

Sangsriratanakul

et al. 2016

The Journal of Veterinary Medical Science

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The capacity of slightly acidic hypochlorous acid water (SAHW), in both liquid and spray form, to inactivate bacteria was evaluated as a potential candidate for biosecurity enhancement in poultry production. SAHW (containing 50 or 100 ppm chlorine, pH 6) was able to inactivate Escherichia coli and Salmonella Infantis in liquid to below detectable levels (≤2.6 log10 CFU/ml) within 5 sec of exposure. In addition, SAHW antibacterial capacity was evaluated by spraying it using a nebulizer into a box containing these bacteria, which were present on the surfaces of glass plates and rayon sheets. SAHW was able to inactivate both bacterial species on the glass plates (dry condition) and rayon sheets within 5 min spraying and 5 min contact times, with the exception of 50 ppm SAHW on the rayon sheets. Furthermore, a corrosivity test determined that SAHW does not corrode metallic objects, even at the longest exposure times (83 days). Our findings demonstrate that SAHW is a good candidate for biosecurity enhancement in the poultry industry. Spraying it on the surfaces of objects, eggshells, egg incubators and transport cages could reduce the chances of contamination and disease transmission. These results augment previous findings demonstrating the competence of SAHW as an anti-viral disinfectant.

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Back to basics

Cited by 32 publications

References 92 publications

Knowledge and practice of hand hygiene among hospitalised patients in a tertiary general hospital in China and their attitudes: a cross-sectional survey

Knowledge and practice of hand hygiene among hospitalised patients in a tertiary general hospital in China and their attitudes: a cross-sectional survey

Early immune anergy towards recall antigens and mitogens in patients at onset of septic shock

Inactivation of bacteria on surfaces by sprayed slightly acidic hypochlorous acid water: <i>in vitro</i> experiments

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