Bacterial cellulose-based dressings with photothermal bactericidal activity and pro-angiogenic ability for infected wound healing

Wu, Yan; Jia, Dong‐Xu; Lu, Kunyan; Zhang, Haixin; Liu, Chunxia; Lin, Yuancheng; Cheng, Jingjing; Zou, Yi; Xu, Huibin; Chen, Hong; Zhang, Yanxia; Yu, Qian

doi:10.1016/j.jmst.2023.04.005

Cited by 37 publications

(8 citation statements)

References 60 publications

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“…This effect can be attributed to the released Cu 2+ ions from QC NPs, as they are reported to have the ability to upregulate expression of vascular endothelial growth factor and promote neovascularization. 58–60 In addition, when compared to the BC group, the BQC 200 group exhibited improved organization of collagen fibers (Fig. 7i) and a higher percentage of collagen deposition (Fig.…”

Section: Resultsmentioning

confidence: 90%

Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Cheng,

Zhang,

et al. 2024

Biomater. Sci.

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Section: Resultsmentioning

confidence: 90%

Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Cheng,

Zhang,

et al. 2024

Biomater. Sci.

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“…Different scaffolds were incubated with a protease XIV solution (2 U/mL in PBS, Sigma-Aldrich, St. Louis, MO) for 24 h to evaluate the in vitro degradation behavior. At the designed time points (1,2,4,8,12, and 24 h), the samples were washed with distilled water, dried at 60 °C for 24 h, and weighed. Six samples were measured for each group.…”

Section: Preparation Of Different Scaffoldsmentioning

confidence: 99%

“…Skin wounds are common due to burns, traffic accidents, tumors, and diabetes . Wound dressings are widely used to protect wounds and favor skin regeneration. − Synthetic and natural biopolymers have been fabricated to form skin grafts with niches supportive of wound healing. − Chemical signals (e.g., growth factors, exosomes, inhibitors, bioactive drugs) and physical cues (e.g., stiffness, nanomicromorphologies, aligned topography) influence cell behavior and have been introduced to wound dressings to accelerate wound healing. − However, the challenge remains to optimize multiple cues simultaneously in these types of materials in order to optimize skin regeneration.…”

Section: Introductionmentioning

confidence: 99%

Silk Nanofiber Scaffolds with Multiple Angiogenic Cues to Accelerate Wound Regeneration

Xu,

Xiao,

Guo

et al. 2023

ACS Biomater. Sci. Eng.

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Niches with multiple physical and chemical cues can influence the fate of cells and tissues in vivo. Simulating the in vivo niche in the design of bioactive materials is a challenge, particularly to tune multiple cues simultaneously in the same system. Here, an assembly strategy was developed to regulate multiple cues in the same scaffold based on the use of two silk nanofiber components that respond differently during the fabrication processes. An aqueous solution containing the two components, amorphous silk nanofibers (ASNFs) and β-sheet-rich silk nanofibers (BSNFs), was sequentially treated with an electrical field and freeze-drying processes where the BSNFs oriented to the electrical field, while the ASNFs formed stable porous structures during the lyophilization process to impact the mechanical properties. Bioactive cargo, such as deferoxamine (DFO), was loaded on the BSNFs to enrich cell responses with the scaffolds. The in vitro results revealed that the loaded DFO and the anisotropic structures with improved mechanical properties resulted in better vascularization than those of the scaffolds without the anisotropic features. The multiple cues in the scaffolds provided angiogenic niches to accelerate wound healing.

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“…However, no material has thus far demonstrated complete resistance to adhesion. Conversely, bactericidal surfaces are designed by incorporating quaternary ammonium derivatives, , cationic polymers, , antimicrobial peptides, , silver nanoparticles (AgNPs), , and other bactericidal agents , onto the material surface to eliminate adhering bacteria. Nevertheless, many bactericidal agents exhibit cytotoxicity, and bacteria often develop resistance to them.…”

Section: Introductionmentioning

confidence: 99%

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

Qu,

Zou,

Wang

et al. 2024

ACS Appl. Mater. Interfaces

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Biofilm contamination presents a significant threat to public health, the food industry, and aquatic/marine-related applications. In recent decades, although various methods have emerged to combat biofilm contamination, the intricate and persistent nature of biofilms makes complete eradication challenging. Therefore, innovative alternative solutions are imperative for addressing biofilm formation. Instead of solely focusing on the eradication of mature biofilms, strategically advantageous measures involve the delay or prevention of biofilm formation on surfaces. Quorum sensing, a communication system enabling bacteria to coordinate their behavior based on population density, plays a pivotal role in biofilm formation for numerous microbial species. Materials possessing antibiofilm properties that target quorum sensing have gained considerable attention for their potential to prevent biofilm formation. This Review consolidates recent research progress on the utilization of materials with antiquorum sensing properties for combating biofilm formation. These materials can be categorized into three distinct types: (i) antibiofilm nanomaterials, (ii) antibiofilm surfaces, and (iii) antibiofilm hydrogels with antiquorum sensing capabilities. Finally, the Review concludes with a brief discussion of current challenges and outlines potential avenues for future research.

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Bacterial cellulose-based dressings with photothermal bactericidal activity and pro-angiogenic ability for infected wound healing

Cited by 37 publications

References 60 publications

Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Bi-functional quercetin/copper nanoparticles integrating bactericidal and anti-quorum sensing properties for preventing the formation of biofilms

Silk Nanofiber Scaffolds with Multiple Angiogenic Cues to Accelerate Wound Regeneration

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

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