Bacterial Etiologies and Antibiotic Susceptibility Pattern of Urinary Tract Infections at the Pediatric Ward of Dastgheib Hospital, Shiraz, Iran: A Three-Year Study (2009 - 2011)

Motamedifar, Mohammad; Zamani, Khosro; Hassanzadeh, Yashgin; Pashoutan, Sajedeh

doi:10.5812/archcid.28973

Cited by 7 publications

(3 citation statements)

References 16 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results were consistent with other studies that showed that UTI was more frequent in females [ 5 , 13 , 15 , 16 ]. High frequency of UTI in females can be due to anatomical differences such as shortness of urethra and close space between the anus and urethral orifice [ 17 , 18 ]. However, some studies reported that UTI at an early age (<2 years) is greater in boys than that in girls [ 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

A decade of trends in the distribution and antimicrobial susceptibility of prevalent uropathogens among pediatric patients from Tehran, Iran during 2005–2016

Nateghian

Karaji

Zamani

2021

Asian Journal of Urology

View full text Add to dashboard Cite

Objectives To determine changes in the distribution of uropathogens and their antimicrobial resistance in pediatric patients in a children's hospital from 2005 to 2016. Methods A cross-sectional analysis of uropathogens and their antimicrobial resistance within inpatient children was performed over the 11-year period, 2005 to 2016, in Ali Asghar children's hospital. The rate of antibiotic resistance among patients was evaluated according to demographic data including age, sex, urinary tract abnormities and history of antibiotic consumption. Results In total, 958 female and 349 male positive cultures were analyzed. Escherichia coli ( E. coli ) (77.6%) was the most common causative agent of urinary tract infection (UTI) in children and Klebsiella pneumoniae (10.4%), Pseudomonas aeruginosa (2.4%), and Enterococcus spp (2.4%) were less frequent isolated bacteria. The resistance rates of E. coli isolates were increased against amikacin, ceftriaxone, ceftazidime, ciprofloxacin, cotrimoxazole and imipenem from 2005 to 2010. However, we observed a decreasing trend for some of antibiotics including amikacin, gentamicin, imipenem, ceftazidime and cotrimoxazole during 2014–2016. The rate of antibiotic resistance was greater in boys than in girls against many antibiotics. The rate of resistance to amikacin, gentamicin, nitrofurantoin and cotrimoxazole in patients aged <1 year was higher than other age groups ( p <0.001). A higher antibiotic resistance rate was observed in patients with anatomical abnormality and those who have had a history of antibiotic consumption. Conclusion The study indicated the significant decrease in E. coli antibiotic resistance in the last 3 years. An effective empirical treatment regime should be based on local epidemiology and antimicrobial susceptibility testing.

show abstract

Section: Discussionmentioning

confidence: 99%

A decade of trends in the distribution and antimicrobial susceptibility of prevalent uropathogens among pediatric patients from Tehran, Iran during 2005–2016

Nateghian

Karaji

Zamani

2021

Asian Journal of Urology

View full text Add to dashboard Cite

show abstract

“…In the present study, 63% of the enrolled cases were male ( P =0.030), and no significant difference was observed in the incidence rate of UTI in the male and female in the UTI cases. Nevertheless, most of the studies on pediatric UTI indicate that the incidence of UTI in females is more than in males, other than the neonatal group ( 28 ).…”

Section: Discussionmentioning

confidence: 99%

Etiology and Antimicrobial Susceptibility Pattern of Urinary Tract Infection in the First Year after Pediatric Renal Transplantation: A Preliminary Study

Sayyahfar

Mohammadnezhad

Zamani

et al. 2023

Med. J. Islam. Republ. Iran

View full text Add to dashboard Cite

Background: Urinary tract infection (UTI) is common after pediatric renal transplantation, and the emergence of multidrug-resistant (MDR) bacteria causing UTI is a therapeutic challenge in this regard. The main purpose of this study was to determine the UTI frequency, its etiologic agents, and the antibiotic susceptibility pattern in the first year following renal transplantation in Iranian pediatric recipients.Methods: In a retrospective cohort study, all of the 81 children who had undergone renal transplantation in Hazrat Rasoul Akram Hospital between 2012 and 2017 were enrolled. Confirmed episodes of UTI during the first year following renal transplantation were analyzed. The pattern of antibiotic resistance was determined for the causative agents of UTI. The data were analyzed using the IBM SPSS Statistics software (version 20). and the P < 0.05 was considered significant.Results: Totally, from 81 enrolled cases, 37(44.7%) cases were in the age group of 11-15 years. Overall, 19, 10, and 3 UTI episodes had occurred in the first month, from the first to sixth month, and between the sixth month and one year after transplantation, respectively. The four most common isolated bacteria were Escherichia coli (E. coli; 31.2%), Pseudomonas aeruginosa (P. aeruginosa; 25%), Enterococci (21.9%) and Klebsiella pneumoniae (K. pneumoniae; 12.5%). The highest rate of resistance was reported to trimethoprim/sulfamethoxazole (TMP/SMX), cephalosporins, and fluoroquinolones among gram-negative bacteria. However, none of the Enterococci isolates were resistant to linezolid and nitrofurantoin.Conclusion: Resistance to antibiotics is increasing among the pathogens causing UTI in pediatric renal transplanted cases. It is suggested to stop the administration of TMP/SMX and third-generation cephalosporins for empiric treatment of UTI in Iranian pediatric renal transplant recipients. Ciprofloxacin might be administered cautiously secondary to the increasing rate of antibiotic resistance in this group.

show abstract

“…Variation exist between patterns of sensitivity and resistance regarding different microorganisms and antibiotics in different regions of the world so it is always advisable to keep up to date with the recent trends. 5,6 A study found sensitivity of ceftriaxone as 44.5%, ciprofloxacin 32.7%, gentamycin 45.5% and ofloxacin 24.5% in children with UTIs. 7 While results of urine culture and sensitivity is awaited, treating suspected children with UTI adopting empirical antibiotic treatment is a usual management practice.…”

mentioning

confidence: 99%

Sensitivity of ciprofloxacin and ceftriaxone in children with urinary tract infections

et al. 2020

View full text Add to dashboard Cite

Background: Urinary tract infections (UTIs) are the 2nd commonest bacterial infections, after respiratory tract infections (RTIs), and may go on to progress into chronic kidney disease among paediatric population. The objective of this study was to determine frequency of sensitivity of ciprofloxacin and ceftriaxone in children with urinary tract infections (UTIs).Methods: This descriptive, cross-sectional study was done at the department of pediatric medicine, Nishtar Hospital, Multan, from 10th August 2019 to 9th January 2020. A total of 165 patients presenting with UTI and aged 2 to 12 years of either gender were included. Urine sample was taken in sterilized container and sent immediately for urine culture and sensitivity tests.Results: In a total of 165 cases, mean age was 5.15±2.50 years while most cases, 113 (68.48%) were between 2 to 6 years of age. Out of the 165 patients, 112 (67.87%) were female representing female to male ratio of 2.1:1. Sensitivity of ciprofloxacin in 53 (32.12%) and ceftriaxone in 107 (64.85%) patients was found.Conclusions: This study showed the sensitivity of ciprofloxacin in 32.12% and ceftriaxone in 64.9% children with UTIs.

show abstract

Bacterial Etiologies and Antibiotic Susceptibility Pattern of Urinary Tract Infections at the Pediatric Ward of Dastgheib Hospital, Shiraz, Iran: A Three-Year Study (2009 - 2011)

Abstract: Background: Urinary tract infection (UTI) is one of the most common infections in children. Timely diagnosis and appropriate treatment of UTI requires knowledge of etiologic agents and antibiotic resistance pattern of common uropathogens.

Cited by 7 publications

References 16 publications

A decade of trends in the distribution and antimicrobial susceptibility of prevalent uropathogens among pediatric patients from Tehran, Iran during 2005–2016

A decade of trends in the distribution and antimicrobial susceptibility of prevalent uropathogens among pediatric patients from Tehran, Iran during 2005–2016

Etiology and Antimicrobial Susceptibility Pattern of Urinary Tract Infection in the First Year after Pediatric Renal Transplantation: A Preliminary Study

Sensitivity of ciprofloxacin and ceftriaxone in children with urinary tract infections

Contact Info

Product

Resources

About