Bacterial infection in the fetus and newborn.

Neonatal Omphalitis in Iraq

“…This is in agreement with reports from Middle East [7,8,16]. This study also shows low birth weight as a risk factor of Omphalitis because; there is a significant association between low birth weight and Omphalitis (P< 0.001), this finding agrees with Davies [17] who reports that low birth weight has an important role in the genesis of Omphalitis in both hospital and home-born neonates. This study found that the associated between the Umbilical catheterization and Omphalitis was only 2(3.1%) cases of Omphalitis so it was not significant factor in this study.…”

“…This finding agrees with Guvenc [8] who found that the umbilical catheterization has no significant association with Omphalitis in Eastern Turkey. This finding also disagrees with the finding of Davies [17] who reported that the risk factors for neonatal Omphalitis were included low birth weight, home delivery and prior umbilical catheterization, this may be due to that the report was presented at 1972 which was enough time to developed the country in aseptic delivery techniques, hygienic cord care and prompt antimicrobial therapy [6,10].…”

Incidence of morbidity and mortality in neonate born to mothers with premature rupture of membranes

“…Early onset bacterial infections occur either due to ascending infection following rupture of membranes or during the passage of baby through infected birth canal. 5 PROM of duration more than 18 hours is the appropriate cut-off for increased risk of neonatal infection. 6 There are recommendations of antenatal antibiotic administration in pregnant women who had PROM ≥18 hours but the regimen to prevent postnatal neonatal infection still varies among institutions.…”

Ampicillin and gentamicin in the treatment of fetal intrauterine infections

“…viridans in 23.7 per cent and nonhaemolytic streptococci in 8.7 per cent. Other authors [6] report the predominance of the Gram negative organisms in cases of intrauterine infections.…”

“…The Optimum clinical results are obtained by the administration of the appropriate antibiotic, which reaches an adequate level in the amniotic fluid and cord serum. Due to the increasing use of ampicillin and gentamicin for fetomaternal infections and prophylaxis [6,10,16], we investigäted the concentration of these antibiotics in the maternal serum, amniotic fluid and cord serum. The observed levels were compared with the minimal inhibitory concentration of the offending pathogens in the amniotic fluid and cord serum in cases of fetal intrauterine infections.…”