Incidence of morbidity and mortality in neonate born to mothers with premature rupture of membranes

Lokhande, Sumant; Nistane, Rajendra

doi:10.18203/2349-3291.ijcp20163685

Cited by 5 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When the duration of PROM was <24 hours, sepsis was seen in 1.16 % cases in our study compared to 9.8% in the study by Patil et al 20 and no sepsis in studies by Lokhande et al 19 and Ramesh TV et al 16 .…”

Section: Discussioncontrasting

confidence: 63%

“…When the duration of PROM was <24 hours, 15.1% neonates had respiratory distress in our study compared to 37.5% in the study by Lokhande et al 19 , 37.5% in the study by Ramesh TV et al 16 and 28.6% in the study by Patil et al 20 . When the duration of PROM was 24-72 hours, 64% neonates had respiratory distress in our study compared to 13% in the study by Lokhande et al 19 , 18.5% in the study by Ramesh TV et al 16 and 20% in the study by Patil et al 20 .…”

Section: Discussioncontrasting

confidence: 56%

See 1 more Smart Citation

Outcome of neonates born to mothers with premature rupture of membranes

Reddy

Kher

2020

Sri Lanka J Child Health

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 63%

Section: Discussioncontrasting

confidence: 56%

Outcome of neonates born to mothers with premature rupture of membranes

Reddy

Kher

2020

Sri Lanka J Child Health

View full text Add to dashboard Cite

show abstract

“…65% of women had vaginal delivery and 35% caesarean section. They also observed that Respiratory distress syndrome was the most common complication (36.7%) followed by septicemia (8.3%), meningitis (1.7%) and pneumonia (1.7%) [16]. Another study also reported similar results with maximum patients of PPROM (59.0%) belonging to 21-25 years age group with mean age of 23.52±3.70 years.…”

Section: Original Research Articlesupporting

confidence: 52%

Preterm pre-labor rupture of membranes and perinatal outcome: a prospective cohort study

Kumar

Yadav

2019

Obs Gyne Reivew J Obstet Gynecol

View full text Add to dashboard Cite

Background: Preterm Prelabor Rupture of Membranes (PPROM) is one of the common causes of increased perinatal morbidity and mortality. Objectives: To know the perinatal outcome in antenatal women with Preterm Prelabor Rupture of Membranes. Methods: Present prospective cohort study was conducted in rural tertiary center of Northern India over one year (January-December 2018) on 75 antenatal women at gestation ≥28 weeks with Preterm Prelabor Rupture of Membranes. Onset of labor and mode of delivery was recorded in all participants. Immediately after birth, neonatal Apgar scores, birth weight, gender, NICU admission, need for oxygen or intubation, complications and perinatal mortality (early neonatal deaths and stillbirths) were recorded. Results: Of total 3,085 deliveries (at gestation ≥28 weeks) during the study period, 75 (2.4%) antenatal women had PPROM, of which 72 (96.0%) had preterm delivery and three (4.0%) were managed conservatively and delivered atterm. Four (5.6%) had iatrogenic preterm delivery (labor was induced) due to feto-maternal risk factors and 68(94.4%) went into spontaneous preterm labor. The most common mode of delivery was vaginal (81.3%) followed by Lower segment cesarean section (18.7%). Of 75 neonates delivered, 70 (93.3%) were live, 03(4.0%) stillbirths and 02(2.7%) early neonatal deaths. The mean neonatal birth weight was 2.02±0.50 Kg (p=0.000). Sixty-seven (89.3%) neonates had poor 1-minute Apgar scores, 17(22.7%) had 5-minutes Apgar score <7, 40 (53.3%) required NICU admission, 06(8.0%) intubated, 45(60.0%) developed neonatal complications. The most common neonatal complication was prematurity (58.7%) followed by Respiratory distress syndrome (44.0%). Conclusion: Preterm Prelabor Rupture of Membranes was significantly associated with adverse perinatal outcome.

show abstract

“…Several other workers have reported similar finding. [5][6][7][8] Bias for male sex, place of study, sample including other factors may be responsible for increased number of male cases in these studies. Though the exact reason for this male preponderance is not known with certainty, it is probably due to the fact that the factors regulating the synthesis of Y-globulins are situated on the X-chromosome.…”

Section: Discussionmentioning

confidence: 99%

“…15,16 The present study also found increased incidence of PROM in term gestation (53%), this results are consistent with Lokhande et al, study. 8 Total 54 neonates were blood culture positive, giving a positivity rate of 60%, where most predominant microorganism grown was klebsiella, followed by E. coli and staphylococcus aureus. This result was comparable with the other studies.…”

Section: Discussionmentioning

confidence: 99%

A study of bacteriological profile and outcome of babies born to mother with Premature rupture of membrane and its correlation with blood and gastric culture

Kamble

Nagargoje

Chopde

2019

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: PROM, a condition that occurs when fetal membranes are ruptured at least one hour before onset of labor. While PROM is observed in 10% of all pregnancies, 60-80% of PROM is observed in term and 20-40% in pregnancies less than 37th gestational week. PROM is the most significant reason for preterm labor. The three causes of neonatal death associated with PROM are prematurity, sepsis and pulmonary hypoplasia. Infants born with sepsis have a mortality rate four times higher than those without sepsis. Objective of the study was correlation of blood and gastric culture positive sepsis in PROM newborns. It helps to find out the incidence of PROM in our locality.Methods: This retrospective study enrolled 90 neonates born to healthy mothers with history of PROM more than 18 hours duration, admitted in SNCU/ward at a tertiary care hospital for six months duration from 1st January 2017 to 30 June 2017. Clinical profile of these Newborn with history of PROM was noted such as birth weight, gender, gestation, duration of membrane rupture, history of maternal fever. For all newborns with PROM, sepsis screen had been sent. The neonatal outcome was also recorded, and the data was collected and analyzed by using frequency and percentages.Results: Gram negative bacilli were the commonest cause of neonatal sepsis and male neonates were more prone to infection. PROM and low birth weight especially, ELBW and VLBW are the common high-risk factors for early onset sepsis. Most common organisms isolated in blood and gastric culture were Klebsiella and Staphylococcus aureus respectively.Conclusions: PROM is a high-risk obstetric condition. Active management is needed to enable delivery within 24 hours of PROM as it offers better neonatal outcome. Morbidity and mortality increase as the duration of PROM increases. This can be reduced by early diagnosis, specific treatment and strict infection control practices in neonatal units.

show abstract

Incidence of morbidity and mortality in neonate born to mothers with premature rupture of membranes

Cited by 5 publications

References 5 publications

Outcome of neonates born to mothers with premature rupture of membranes

Outcome of neonates born to mothers with premature rupture of membranes

Preterm pre-labor rupture of membranes and perinatal outcome: a prospective cohort study

A study of bacteriological profile and outcome of babies born to mother with Premature rupture of membrane and its correlation with blood and gastric culture

Contact Info

Product

Resources

About