1997
DOI: 10.1111/j.1439-0442.1997.tb01127.x
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Bacteriological Findings, Blood Chemistry Profile and Plasma Endotoxin Levels in Bitches with Pyometra or other Uterine Diseases

Abstract: Summary Uteri from 60 bitches with a clinical diagnosis of pyometra, or with an enlarged uterus as revealed radiographically or ultrasonographically, underwent histopathological examination, at which a diagnosis of pyometra was established in 48 of the 60 (80%) cases. Escherichia coli was isolated from 43 (90%) of the 48 uteri with pyometra. In 8 of the 60 cases, other pathological uterine conditions, such as endometrial hyperplasia, adenomyosis, mucometra or hydrometra, were diagnosed histopathologically. No … Show more

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Cited by 85 publications
(72 citation statements)
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“…Subsequently, we wanted to discover whether suppression of phagocytosis-induced oxidative burst was caused by impaired ability to recognise lipopolysaccharide (LPS) by TLR4 because LPS is the main component of the outer membrane of E. coli, the most common bacterial agent associated with canine pyometra (Fransson et al 1997;Dhaliwal et al 1999) (Figure 3). Median fluorescence intensity of TLR-expressing neutrophils appeared not to be influenced by oestrogen and progesterone.…”
Section: Toll-like Receptor 4 Expressionmentioning
confidence: 99%
“…Subsequently, we wanted to discover whether suppression of phagocytosis-induced oxidative burst was caused by impaired ability to recognise lipopolysaccharide (LPS) by TLR4 because LPS is the main component of the outer membrane of E. coli, the most common bacterial agent associated with canine pyometra (Fransson et al 1997;Dhaliwal et al 1999) (Figure 3). Median fluorescence intensity of TLR-expressing neutrophils appeared not to be influenced by oestrogen and progesterone.…”
Section: Toll-like Receptor 4 Expressionmentioning
confidence: 99%
“…Its etiology and pathogenesis are complex and only partly understood [11,14,16,17,19]. The most common bacterium isolated in cases of pyometra is Escherichia coli(E. coli) [1,5,8,11,16]. There have been a few studies of resistance to antimicrobials among bacteria isolated from the uteri of bitches with pyometra [4,7,9,15,20].…”
mentioning
confidence: 99%
“…This often occurs in aged animals, and surgery in the affected animals involves high risks because of complications such as renal failure and septic shock, leading to death in some animals [2,9,10]. The etiology of pyometra is mainly Escherichia coli, Klebsiella, Pasteurella and Staphylococcus, most of which are gram-negative bacteria [1,7,10]. However, little is known about the relation between pyometra and endotoxin, which is a constitutive component of gram-negative bacteria.…”
mentioning
confidence: 99%
“…In clinical veterinary medicine, blood endotoxin levels have been reported in bovine gangrenous mammillitis [3] and equine colic [5], but little attention has been paid to blood endotoxin levels in small animals [1,4,14].…”
mentioning
confidence: 99%
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