Bacteriology: Salmonella (sero)types and their resistance patterns in pig faecal and post‐mortem samples

Wolf, P.J. van der; Peperkamp, N. H. M. T.

doi:10.1080/01652176.2001.9695108

Cited by 8 publications

(6 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2003) or global surveys carried out on bacterial isolates from diagnostic submissions or indicator bacteria collected from faecal content at slaughter (Van den Bogaard et al. 2000; Van der Wolf and Peperkamp 2001; DANMAP 2002). To our knowledge, the impact of administration of quinolones to pigs on development of resistance has not been documented in the field at the herd level.…”

Section: Introductionmentioning

confidence: 99%

Effect of quinolone treatment on selection and persistence of quinolone-resistant Escherichia coli in swine faecal flora

Belloc¹,

Lam²,

Pellerin³

et al. 2005

J Appl Microbiol

View full text Add to dashboard Cite

Aims: To study the effect of oral administration of a quinolone on emergence of resistance in an indicator bacterial species from faecal flora. Methods and Results: Quinolone resistance was studied in Escherichia coli obtained from the faecal contents of pigs housed in nine commercial farrow-to-finish herds in France after administration of flumequine to sows. The percentage of quinolone-resistant E. coli increased in the faeces of sows after administration of flumequine (mean 21AE78% at day 7 vs 6AE42% before treatment for nalidixic acid) and then decreased (mean 12AE6 and 10AE4 at days 30 and 60, respectively for nalidixic acid), being not significantly different from initial values 1 month post-treatment. In young pigs, the proportion of resistant strains was lower and decreased over rearing period. Moreover, changes over time of both total E. coli and the proportion of resistant bacteria exhibited great inter-individual variability. Conclusions: Restoration of susceptible faecal flora occurred within 2 months after flumequine treatment. Significance and Impact of the Study: Effect of flumequine treatment of sows on the quinolone resistance of faecal E. coli of both sows and their progeny is noticeable but transitory.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of quinolone treatment on selection and persistence of quinolone-resistant Escherichia coli in swine faecal flora

Belloc¹,

Lam²,

Pellerin³

et al. 2005

J Appl Microbiol

View full text Add to dashboard Cite

show abstract

“…In order to reduce the potential risk to consumers, it is crucial to minimize pathogen intake into the food chain. In the European Union, surveillance systems are required (regulation [EC] 2160/2003; http://europa.eu.int/eur-lex/pri/en/oj/dat/2003 /l_325/l_32520031212en00010015.pdf), and a number of countries are specifically monitoring the occurrence of Salmonella in the pork production chain (2,11,19,45,48). In pigs, Sal-monella monitoring is based on meat juice serology (26).…”

mentioning

confidence: 99%

Immunization of Pigs To Prevent Disease in Humans: Construction and Protective Efficacy of a Salmonella enterica Serovar Typhimurium Live Negative-Marker Vaccine

Selke¹,

Meens²,

Springer³

et al. 2007

Infect Immun

View full text Add to dashboard Cite

Zoonotic infections caused by Salmonella enterica serovar Typhimurium pose a constant threat to consumer health, with the pig being a particularly major source of multidrug-resistant isolates. Vaccination, as a promising approach to reduce colonization and shedding, has been scarcely used, as it interferes with current control programs relying on serology as a means of herd classification. In order to overcome this problem, we set out to develop a negative-marker vaccine allowing the differentiation of infected from vaccinated animals (DIVA). Applying an immunoproteomic approach with two-dimensional gel electrophoresis, Western blot, and quadrupole time-of-flight tandem mass spectrometry, we identified the OmpD protein as a suitable negative marker. Using allelic exchange, we generated an isogenic mutant of the licensed live vaccine strain Salmoporc and showed that virulence of Salmoporc and that of the mutant strain, Salmoporc⌬ompD, were indistinguishable in BALB/c mice. In a pig infection experiment including two oral immunizations with Salmoporc⌬ompD and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of Salmoporc⌬ompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract. OmpD immunogenic epitopes were determined by peptide spot array analyses. Upon testing of several 9-mer peptides, each including an immunogenic epitope, one peptide (positions F 100 to Y 108 ) that facilitated the detection of infected animals independent of their vaccination status (DIVA function) was identified. The approach described overcomes the problems currently limiting the use of bacterial live vaccines and holds considerable potential for future developments in the field.

show abstract

“…Dadurch verändert sich der pH-Wert im Darm, was auch einen Selektionsdruck auf die Magen-Darm-Flora bedeutet. Kommen Stress durch ein schlechtes Tier-Fressplatz-Verhältnis oder antibiotische Behandlungen hinzu, besteht die Gefahr einer Dysbiose, bei der sich Salmonellen, E. coli oder andere fakultativ pathogene Erreger selektiv vermehren können (5,25). Untersuchungen von Papenbrock (16) und Visscher (27)…”

Section: Gründe Für Die Steigende Salmonellenprävalenzunclassified

Salmonellen im Schweinebestand

Rostalski¹

2015

Tierarztl Prax Ausg G

View full text Add to dashboard Cite

The goal of reducing salmonella prevalence in slaughter pigs using a monitoring system is difficult to realize. Many of the category-III-farms have proper hygiene and clinical signs are often lacking, which makes the implementation of sustainable counselling concepts difficult. The improvement of biological performances and the changes in sow keeping and feeding concepts lays the focus on the breeding and farrowing units. Information on the salmonella status of the delivering pig farms is essential for establishing, for example, vaccination programs. A general inspection duty for all pig-producing units beginning with the breeding herds is reasonable. To achieve this, measurements for stress reduction, changes of the current detection systems and early information of farms with an acute salmonella problem are discussed.

show abstract

Bacteriology: Salmonella (sero)types and their resistance patterns in pig faecal and post‐mortem samples

Abstract: Assessment of neutrophil function in the dairy cow during the perinatal period. J Vet Med 1988; 35: 747-51

Cited by 8 publications

References 17 publications

Effect of quinolone treatment on selection and persistence of quinolone-resistant Escherichia coli in swine faecal flora

Effect of quinolone treatment on selection and persistence of quinolone-resistant Escherichia coli in swine faecal flora

Immunization of Pigs To Prevent Disease in Humans: Construction and Protective Efficacy of a Salmonella enterica Serovar Typhimurium Live Negative-Marker Vaccine

Salmonellen im Schweinebestand

Contact Info

Product

Resources

About