2009
DOI: 10.1111/j.1439-0272.1988.tb00724.x
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Balano-Preputial Separation as an External Sign of Puberty in the Rat: Correlation with Histologic Testicular Data/Balano-praeputial-Trennung als ein äußeres Zeichen der Pubertät für die Ratte: Korrelation mit histologischen Daten

Abstract: Summary: In order to correlate the date of balano‐preputial separation (BPS) with the testicular development, twenty four rats were selected from an experimental design focused on the effects of pituitary grafts on puberty. Animals that presented BPS at an early age, showed a smaller volume of the seminiferous epithelium and a lower spermatogenic level than that presented BPS at a more advanced age. These data indicate that the advancement in BPS induced by pituitary grafts was not in keeping with an equivale… Show more

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Cited by 13 publications
(2 citation statements)
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“…Pubertal onset is thought to be primarily driven by increased testosterone production in males and one well-established external marker of pubertal development in rodents is preputial separation (PS) [ 25 , 37 , 38 ]. Therefore, as a further test of the hypothesis that hormone signaling is disrupted in DKO males, we next documented the timing of PS.…”
Section: Resultsmentioning
confidence: 99%
“…Pubertal onset is thought to be primarily driven by increased testosterone production in males and one well-established external marker of pubertal development in rodents is preputial separation (PS) [ 25 , 37 , 38 ]. Therefore, as a further test of the hypothesis that hormone signaling is disrupted in DKO males, we next documented the timing of PS.…”
Section: Resultsmentioning
confidence: 99%
“…Pubertal onset is thought to be primarily driven by increased testosterone production in males and one well established external marker of pubertal development in rodents is preputial separation (PS) (Gaytan et al, 1988; Hoffmann, 2018; Korenbrot et al, 1977). Therefore, as a further test of the hypothesis that hormone signaling is disrupted in DKO males, we next documented the timing of PS in WT and DKO males.…”
Section: Resultsmentioning
confidence: 99%