“…Both sexes generally showed relatively large amounts of variation in the distribution of cortical bone, indicated through measures of circularity of the periosteal and endosteal margins (Figure ). High variability in metatarsal cross‐sectional shape may be the result of many factors, including differences in gait patterns, foot wear, foot shape and musculature (e.g., arch collapse; Franklin, Grey, Heneghan, Bowen, & Li, ), muscular fatigue threshold (Arndt, Ekenman, Westblad, & Lundberg, ), and the presence of soft tissue pathology such as hallux valgus (Mann & Coughlin, ), all of which may impact biomechanics. Particularly, individuals with metatarsal pronation, diagnosed by an angular shift in position of the inferior tuberosity at the metatarsal base, may show different cross‐sectional shapes, perhaps related to associated biomechanical changes: metatarsal pronation is highly correlated with collapse of the medial longitudinal arch and is known to predispose individuals to hallux valgus (Eustace et al, ).…”