Existing knowledge from the literature demonstrates that primary prevention of diabetes complications is possible. However, patient-, provider-, and health system-based barriers may prevent implementation of evidence-based practices. This article explores barriers to diabetes care that are external to the patient and that may require particular attention when attempting to translate primary prevention strategies into clinical care in the community.Results from landmark clinical studies demonstrate that the complications of diabetes can be prevented or delayed by controlling risk factors such as hyperglycemia, 1,2 hypertension, 3,4 and hyperlipidemia. 5,6 Despite knowledge gained through these studies, adherence to established evidence-based treatment guidelines aimed at controlling these risk factors and utilization of preventive care services by both providers and patients are low. This ultimately may result in patient outcomes that are less than optimal. The solution to the lack of adherence by both providers and patients is not to lay blame, but rather to investigate the factors or barriers underlying nonadherence.Several factors are hypothesized to contribute to nonadherence, including patient-, provider-, and health care system-based issues. These factors are outlined in Figure 1.Preventive health care is the cornerstone of primary and secondary prevention of diabetes complications.