Basal Cell Carcinoma of the Prostate: A Case Report

Stearns, Gillian; Cheng, Jed-Sian; Shapiro, Oleg; Nsouli, Imad

doi:10.1016/j.urology.2012.03.003

Cited by 9 publications

(9 citation statements)

References 5 publications

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“…Beneath the secretory lining is a layer of basal cells as well as interspersed endocrine‐paracrine cells . Basal cell carcinoma of the prostate was first reported in 1974, and can be classified as adenoid cystic or basaloid cell origin . Histologically, infiltrating basaloid cells form dilated acinar cribriform spaces with admixed glandular or trabecular material .…”

Section: Discussionmentioning

confidence: 99%

Primary basal cell carcinoma of the prostate with concurrent adenocarcinoma

et al. 2020

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Introduction Prostatic basal cell carcinoma is an extremely rare tumor, exhibiting various histopathological features and clinical spectrums of disease. Case presentation A 69‐year‐old male presented to our department with 2 years of voiding difficulty and intermittent macroscopic hematuria. With a presumed diagnosis of benign prostatic hyperplasia, he underwent a transurethral resection of the prostate. Pathological examination revealed atypical basaloid cells forming solid nests. Robot‐assisted radical prostatectomy was subsequently performed, confirming a diagnosis of basal cell carcinoma with coexisting acinar adenocarcinoma. Conclusion Although more cases of basal cell carcinoma are indolent than aggressive, there is no reliable method of differentiation between these presentations. Thus, we recommend radical surgery and 6‐monthly disease surveillance until more is discovered about this very rare malignancy.

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Section: Discussionmentioning

confidence: 99%

Primary basal cell carcinoma of the prostate with concurrent adenocarcinoma

et al. 2020

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“…Previous reports on PBCC have noted a mean age of 50–64 years, but a wide age range from 28 to 78 years has been described. Although categorized as prostate cancer, most patients show normal PSA levels [2, 4, 7-10]. PBCC usually shows heterogeneity, like prostate adenocarcinoma, on T2-weighted magnetic resonance imaging (MRI) [11].…”

Section: Discussionmentioning

confidence: 99%

“…Histologically, infiltrating basaloid cells form dilated acinar and cribriform spaces with occasional glandular, trabecular, or solid areas [9, 10]. Stearns et al [10] reported a case of basal cell carcinoma appearing as a neuroendocrine tumor that was treated with etoposide and cisplatin chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…Stearns et al [10] reported a case of basal cell carcinoma appearing as a neuroendocrine tumor that was treated with etoposide and cisplatin chemotherapy. PBCC usually arises from the transitional zone of the prostate, and a pathological diagnosis can be difficult, with immunohistochemical staining typically needed [1].…”

Section: Discussionmentioning

confidence: 99%

“…Radical prostatectomy might be a curative treatment option for localized prostate cancer [10, 14]. Direct invasion to the surrounding organs and liver metastasis have been reported at the time of the diagnosis, so radical prostatectomy was not able to be performed in most cases.…”

Section: Discussionmentioning

confidence: 99%

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Prostate Basal Cell Carcinoma: A Case Report

et al. 2018

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Prostate basal cell carcinoma (PBCC) accounts for 0.01% of all prostate cancers. A 68-year-old man complained of dysuria for 5 years on his initial visit. His PSA level was 3.87 ng/mL. Due to a diagnosis of benign prostate hyperplasia, he underwent transurethral resection of the prostate. A pathological examination revealed that basal cell-like atypical cells made alveolar with palisadal layout. Immunohistochemical analysis showed positive 34β12, P63, and Ki-67. Based on these findings, PBCC was diagnosed. Then, we performed radical prostatectomy. He was free from recurrence 22 months after the operation. We herein report an extremely rare case of PBCC.

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Basal Cell Carcinoma of the Prostate: A Case Report

Cited by 9 publications

References 5 publications

Primary basal cell carcinoma of the prostate with concurrent adenocarcinoma

Primary basal cell carcinoma of the prostate with concurrent adenocarcinoma

Prostate Basal Cell Carcinoma: A Case Report

Primary basal cell carcinoma of the prostate with concurrent acinar adenocarcinoma and ductal adenocarcinoma: A case report and literature review

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