Basal Resistance Against<i>Pseudomonas syringae</i>in<i>Arabidopsis</i>Involves WRKY53 and a Protein with Homology to a Nematode Resistance Protein

Murray, Shane L.; Ingle, Robert A.; Petersen, Lindsay N.; Denby, Katherine J.

doi:10.1094/mpmi-20-11-1431

Cited by 158 publications

(124 citation statements)

References 54 publications

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“…Dual functionality in defense signaling was also observed for AtWRKY53. While Atwrky53 mutants showed delayed symptom development against R. solanacearum, such plants displayed increased susceptibility toward P. syringae (Murray et al, 2007;Hu et al, 2008). Dual functionality was also suggested for AtWRKY41.…”

Section: Wrky Tfs In the Arabidopsis Worldmentioning

confidence: 87%

The Role of WRKY Transcription Factors in Plant Immunity

2009

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Section: Wrky Tfs In the Arabidopsis Worldmentioning

confidence: 87%

The Role of WRKY Transcription Factors in Plant Immunity

2009

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“…WRKY29, WRKY33, and WRKY53, which are induced by Pep1, are reported to be positive regulators of defense responses for bacterial and/or fungal pathogens, such as P. syringae, Botritis cinerea, and A. brassicicola (Asai et al, 2002;Zheng et al, 2006;Murray et al, 2007). WRKY transcription factors bind to W-box DNA elements (C/TTGACC/T) that are found in the promoters of many defense-related genes, including PR-1 and NPR1 (Maleck et al, 2001;Yu et al, 2001;Eulgem and Somssich, 2007).…”

Section: Possible Contribution Of Wrkys To Pep-pepr Systemmentioning

confidence: 99%

PEPR2 Is a Second Receptor for the Pep1 and Pep2 Peptides and Contributes to Defense Responses inArabidopsis

et al. 2010

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Pep1 is a 23-amino acid peptide that enhances resistance to a root pathogen, Pythium irregulare. Pep1 and its homologs (Pep2 to Pep7) are endogenous amplifiers of innate immunity of Arabidopsis thaliana that induce the transcription of defense-related genes and bind to PEPR1, a plasma membrane leucine-rich repeat (LRR) receptor kinase. Here, we identify a plasma membrane LRR receptor kinase, designated PEPR2, that has 76% amino acid similarity to PEPR1, and we characterize its role in the perception of Pep peptides and defense responses. Both PEPR1 and PEPR2 were transcriptionally induced by wounding, treatment with methyl jasmonate, Pep peptides, and pathogen-associated molecular patterns. The effects of Pep1 application on defense-related gene induction and enhancement of resistance to Pseudomonas syringae pv tomato DC3000 were partially reduced in single mutants of PEPR1 and PEPR2 and abolished completely in double mutants. Photoaffinity labeling and binding assays using transgenic tobacco (Nicotiana tabacum) cells expressing PEPR1 and PEPR2 clearly demonstrated that PEPR1 is a receptor for Pep1-6 and that PEPR2 is a receptor for Pep1 and Pep2. Our analysis demonstrates differential binding affinities of two receptors with a family of peptide ligands and the corresponding physiological effects of the specific receptor-ligand interactions. Therefore, we demonstrate that, through perception of Peps, PEPR1 and PEPR2 contribute to defense responses in Arabidopsis.

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“…In addition, HSPRO2 transcripts were lower in both nfxl1 and wrky3 mutant seeds. HSPRO2 is a positive regulator of basal defense against pathogens, as Arabidopsis knockout mutants are more susceptible to P. syringae infection (Murray et al, 2007). HSPRO2 interacts with AKINbg, a subunit of the Sucrose nonfermenting-Related Kinase complex (SnRK1) (Gissot et al, 2006).…”

Section: Link Between Seed Longevity and Genetic Pathways Regulating mentioning

confidence: 99%

Inference of Longevity-Related Genes from a Robust Coexpression Network of Seed Maturation Identifies Regulators Linking Seed Storability to Biotic Defense-Related Pathways

Righetti¹,

Vu²,

Pelletier³

et al. 2015

Plant Cell

121

191

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Seed longevity, the maintenance of viability during storage, is a crucial factor for preservation of genetic resources and ensuring proper seedling establishment and high crop yield. We used a systems biology approach to identify key genes regulating the acquisition of longevity during seed maturation of Medicago truncatula. Using 104 transcriptomes from seed developmental time courses obtained in five growth environments, we generated a robust, stable coexpression network (MatNet), thereby capturing the conserved backbone of maturation. Using a trait-based gene significance measure, a coexpression module related to the acquisition of longevity was inferred from MatNet. Comparative analysis of the maturation processes in M. truncatula and Arabidopsis thaliana seeds and mining Arabidopsis interaction databases revealed conserved connectivity for 87% of longevity module nodes between both species. Arabidopsis mutant screening for longevity and maturation phenotypes demonstrated high predictive power of the longevity cross-species network. Overrepresentation analysis of the network nodes indicated biological functions related to defense, light, and auxin. Characterization of defense-related wrky3 and nf-x1-like1 (nfxl1) transcription factor mutants demonstrated that these genes regulate some of the network nodes and exhibit impaired acquisition of longevity during maturation. These data suggest that seed longevity evolved by co-opting existing genetic pathways regulating the activation of defense against pathogens.

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Basal Resistance AgainstPseudomonas syringaeinArabidopsisInvolves WRKY53 and a Protein with Homology to a Nematode Resistance Protein

Cited by 158 publications

References 54 publications

The Role of WRKY Transcription Factors in Plant Immunity

The Role of WRKY Transcription Factors in Plant Immunity

PEPR2 Is a Second Receptor for the Pep1 and Pep2 Peptides and Contributes to Defense Responses inArabidopsis

Inference of Longevity-Related Genes from a Robust Coexpression Network of Seed Maturation Identifies Regulators Linking Seed Storability to Biotic Defense-Related Pathways

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