Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of intormation, including suggestions for reducing this burden to Department ot Defense, Washington Headquarters Services, Directorate for Information 14. ABSTRACT A deuterium gas-puff load imploded by a multi-MA current driver from a large initial diameter could be a powerful source of fusion neutrons, a plasma neutron source. Unlike the beam-target neutrons produced in Z-pinch plasmas in the 1950s and deuterium-fiber experiments in the 1980s, the neutrons generated in deuterium gas-puffs, with current levels achieved in recent experiments on the SNL Z facility, could contain a substantial fraction of thermonuclear origin. For recent deuterium gas-puff shots ont Z, our analytical estimates and I-D and 2-D simulations predict thermal neutron yields -5 x 1013, in fair agreement with the yields measured on Z. It is demonstrated that the hypothesis of a beam-target origin of the observed fusion neutrons implies a very high Z-pinch-driver-to-fast-ions energy transfer efficiency, 5 to 10%, which would make a multi-MA deuterium Z-pinch the most efficient light-ion accelerator. No matter what mechanism is eventually determined to be responsible for generating fusion neutrons in deuterium gas-puff shots on Z, the neutron yield is shown to scale as y~ I_4 where Im is the peak current of the pinch. Theoretical estimates and numerical modeling of deuterium gas-puff implosions demonstrate that the yields of thermonuclear fusion neutrons that can be produced on ZR and the next generation machines are sufficiently high to make Plasma Neutron Sources (PNS) the most powerful, cost-and energy-efficient laboratory sources of 2.5 to 14 MeV fusion neutron, just like Plasma Radiation Sources (PRS) are the most powerful sources of soft and keV x-rays. In particular, the predicted neutron-producing capability of PNS driven by ZR and ZX accelerators, from -6 x 1016 to _ 1 0 18 matches the projected capability of the NIF laser at thermonuclear energy gains of 1 and 20, respectively.