Basic Data Underlying Clinical Decision Making in Endovascular Therapy

Sullivan, Timothy M.

doi:10.1016/j.avsg.2009.08.001

Cited by 2 publications

(5 citation statements)

References 238 publications

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“…Thrombolytics are less likely to cause complication in later stages of treatment compared with standard treatment which composed of heparin and warfarin therapy. One study observed that the most effective mechanism for thrombolysis was the penetration of the plasminogen activator into the thrombus, followed by activation of plasminogen that binds to fibrin during the clotting process 2 .…”

Section: Discussionmentioning

confidence: 99%

“…One study reported increased rate of serious bleeding and PE after thrombolytic use 24 and out of 12 patients receiving thrombolysis (9 systemic, 3 local); 9 patients on systemic treatment developed PE 1 , 2 . Furthermore, the study revealed that higher doses of thrombolytic were associated with serious adverse events (major bleeding and PE) and these agents can be resulted in better clinical outcome when given in catheter-directed route than systemic administration 21 , 24 .…”

Section: Discussionmentioning

confidence: 99%

“…Primary complications are Pulmonary Embolism (PE) in the short term and Post Thrombotic Syndrome (PTS) in the long term 1 . Standard treatment using propagation, but does not treat the occlusion itself 2 . However, over half of patients may suffer PTS in the long term, manifested by some degree of pain, swelling, skin pigmentation or venous ulceration of the affected leg in the follow up period of therapy despite of taking anticoagulants 3 .…”

Section: Introductionmentioning

confidence: 99%

“…Elastic compression stockings had also been recommended by the American College of Chest Physicians Evidence Based Clinical Practice Guidelines as non-pharmacologic alternative for DVT patients to prevent PTS 4 . However, a meta-analysis (six random controlled trails including 1462 patients) recently indicates that elastic compression stockings are not sufficient to prevent PTS 2 .…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Outcome of Acute Deep Venous Thrombosis Using Standard Treatment versus Thrombolytics: A Literature Review

Yabeyu

Assefa

Beyene

et al. 2019

IJHOSCR

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Deep vein thrombosis (DVT) is a major health problem affectinga significant portion of population. Primary complications are Pulmonary Embolism (PE) in the short term and Post-Thrombotic Syndrome (PTS) in the long term. Thrombolytic drugs act by activating plasminogen which in turn forms the enzyme plasmin. Plasmin consequently degrades blood clots by breaking down the fibrin molecules which make up the clots help to degrade the already formed clot. They can be used using different route of administration, doses and durations. The purpose of this systematic review was to assess the outcome of thrombolytic therapy in terms of the efficacy, safety and effectiveness of the medicines. Electronic searches of databases (MEDLINE and Google Scholar) were queried for articles written in English since 2000 GC. A total of 760 results were obtained using the search keys, and after excluding duplicates, 275 articles were selected. Finally, 9 randomized controlled trials (RCTs) which met the language of publication, study design and exclusion criteria were included in this systematic review. The data were obtained from nine trials (6 countries), providing a study-level data of 1309 participants. Almost all studies revealed that thrombolytic treatment was effective in the management of acute DVT. In most of the studies, the rate of rethrombosis was lower in case of thrombolytic than standard management. Hence, addition of thrombolytic results in persistence and increases the clinical benefits. Thrombolytic therapy was very effective in reversing closed veins, in boosting the patency rate,whilereflux was higher in patients treated with anticoagulants. Thrombolytic offers potential advantages over the standard treatment of DVT by reducing the proportion of patients with chronic disabling leg symptoms (such as PTS) by triple in the longer term. However, the incident of major bleeding was higher in patients receiving thrombolytics than anticoagulants.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Outcome of Acute Deep Venous Thrombosis Using Standard Treatment versus Thrombolytics: A Literature Review

Yabeyu

Assefa

Beyene

et al. 2019

IJHOSCR

View full text Add to dashboard Cite

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“…The use of PPG is not limited to the examination of arterial vessels but is also useful in examining venous vessels. Deep venous thrombosis (DVT) of the lower limbs is a disease affecting approximately 2.5-5% of the general population and carries a high risk of death due to the pulmonary embolism (PE) [30]. Many methods can be used in DVT diagnostics, all of which unfortunately have their limitations [31].…”

Section: Current Application Of Photoplethysmography In Angiology Diamentioning

confidence: 99%

The latest applications of photoplethysmography

et al. 2019

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The development of medicine and the ability to conduct effective therapy in increasingly severe cases create the need to develop new methods of continuous and non-invasive monitoring of the patient's condition. One of the techniques that is widely used in many fields of medicine is photoplethysmography (PPG). The analysis of the latest research indicates that PPG can have much more applications than the measurement of heart rate and arterial saturation of the patient-as shown by the latest research, it can be used in the measurement of many other key parameters. The optimism is the multitude of areas in which PPG monitoring is attempted. There are more and more attempts to use photoplethysmography in diagnosis and evaluation of peripheral vascular diseases, assessment of circulation in diabetic patients and assessment of endothelial function. Authors are focusing on new applications of PPG, its advantages and limitations. Most of them agree that PPG can provide useful knowledge about the patient's condition while being a quick, easy-to-use and cost-effective technique. The following review was created to critically analyze the latest technical developments and uses of PPG in clinical practice. Sources for the following article were found using the PubMed database using keywords such as "photoplethysmography", "oxygen saturation" and "pulse oximeter".

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Basic Data Underlying Clinical Decision Making in Endovascular Therapy

Cited by 2 publications

References 238 publications

Outcome of Acute Deep Venous Thrombosis Using Standard Treatment versus Thrombolytics: A Literature Review

Outcome of Acute Deep Venous Thrombosis Using Standard Treatment versus Thrombolytics: A Literature Review

The latest applications of photoplethysmography

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