Basic Study and Clinical Implications of Left Ventricular False Tendon. Is it Associated With Innocent Murmur in Children or Heart Disease?

Sánchez-Ferrer, Francisco; Ferrer, María Luisa Sánchez; Murcia, María Dolores Grima; Ferrer, Marina Sánchez; Campo, Francisco Sánchez del

doi:10.1016/j.rec.2014.09.021

Cited by 7 publications

(4 citation statements)

References 26 publications

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“…In children with RHD, the mean oxyproline levels were also significantly higher than in the controls (p < 0.01). In healthy children with a history of ARF, the level of OXYP remained significantly higher We include left ventricular false tendon on the list of the HDCT features because we have often seen other signs of CTD in children with HDCT, although Ferrer et al [23] suggested that this is a normal finding in children, with no pathologic consequences except for an innocent murmur.…”

Section: Resultsmentioning

confidence: 99%

Features of heritable disorders of connective tissue in children with acute rheumatic fever and rheumatic heart disease

Boyarchuk

2020

Reumatologia

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Objectives: Heritable disorders of connective tissue (HDCT) are associated with morphological and functional disorders of different organs and systems. The aim of our study was to determine the clinical signs of heritable disorders of connective tissue and oxyproline levels in children with acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Material and methods: A total of 155 patients aged 4 to 17 years participated in the study: 23 with ARF, 78 with RHD, and 54 healthy patients with a history of ARF. All patients underwent a standardized examination protocol, which consisted of a detailed medical history recorded by the physician, general and special laboratory tests, electrocardiogram, echocardiography, and Doppler echocardiography. Special attention was paid to the clinical signs of HDCT. The intensity of the metabolic processes in the connective tissue was evaluated by serum oxyproline levels. Results: The signs of HDCT were revealed in 121 (78.1%) of the patients with ARF and RHD. Among cardiovascular manifestations, we observed mitral valve prolapse most often-in 91 (58.7%) patients. Musculoskeletal anomalies were observed in 94 (60.7%) patients. Both groups of patients with ARF and RHD had elevated mean serum oxyproline levels. Conclusions: Children with acute rheumatic fever and rheumatic heart disease presented with a number of signs characteristic of heritable connective tissue disorders. The cardiovascular and musculoskeletal system changes are the most frequent among all features of HDCT. Elevated levels of serum oxyproline in patients with ARF and RHD confirm connective tissue disorders. Children with manifestations of HDCT are at the risk of ARF and RHD development.

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Section: Resultsmentioning

confidence: 99%

Features of heritable disorders of connective tissue in children with acute rheumatic fever and rheumatic heart disease

Boyarchuk

2020

Reumatologia

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“…Clinical implication of LVFTs is still not well understood although several reports have showed their association with some heart diseases [3]. In order to disclose a potential link between LVFT and heart disease, histologic feature and embryologic development of this entity have been studied.…”

Section: Discussionmentioning

confidence: 99%

“…Although there is no consensus on clinical importance of LVFTs [3], it might be important to visualize the false tendon by cardiac imaging in some cases. In those who undergo heart surgery or left ventricular catheter ablation, the presence of LVFT must be known by the operator to avoid damage to these tendons, in view of the possible presence of the conduction system and coronary artery branches in the tendons [2].…”

Section: Discussionmentioning

confidence: 99%

“…Left ventricular false tendons (LVFTs) are linear fibrous or fibromuscular bands that extend between ventricular septum and papillary muscle, left ventricular free wall, or apex [1, 2]. LVFTs were incidental findings at cadaver dissection in early days, but later technical improvement in the heart imaging such as echocardiography and magnetic resonance imaging let the percentage of LVFT visualization rise [2, 3]. LVFT prevalence in the literature spreads over a wide range, while in the earliest reports, it was 0.5%; current investigations have reported up to 78% [3].…”

Section: Introductionmentioning

confidence: 99%

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Resembling Left Ventricular False Tendon in a Father and His Daughter

Kaplan

Güneş

2018

Case Reports in Cardiology

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Left ventricular false tendons (LVFTs) are linear fibrous or fibromuscular bands stretching across left ventricular cavity. Although LVFTs have been associated with various heart pathologies and investigated embryologically and histologically, there is only one report in the literature connoting possible hereditary transmission of this entity. We reported a father and his daughter having similar types of LVFTs with regard to location and thickness. With this report, we will contribute in the literature in respect to potential genetic inherence of LVFTs.

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Cardiac ventricular false tendons: A meta‐analysis

Carrasco,

Cabrito,

Montalbano

et al. 2023

Clinical Anatomy

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Ventricular false tendons are fibromuscular structures that travel across the ventricular cavity. Left ventricular false tendons (LVFTs) have been examined through gross dissection and echocardiography. This study aimed to comprehensively evaluate the prevalence, morphology, and clinical importance of ventricular false tendons using a systematic review. In multiple studies, these structures have had a wide reported prevalence ranging from less than 1% to 100% of cases. This meta‐analysis found the overall pooled prevalence of LVFTs to be 30.2%. Subgroup analysis indicated the prevalence to be 55.1% in cadaveric studies and 24.5% in living patients predominantly studied by echocardiography. Morphologically, left and right ventricular false tendons have been classified into several types based on their location and attachments. Studies have demonstrated false tendons have important clinical implications involving innocent murmurs, premature ventricular contractions, early repolarization, and impairment of systolic and diastolic function. Despite these potential complications, there is evidence demonstrating that the presence of false tendons can lead to positive clinical outcomes.

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Basic Study and Clinical Implications of Left Ventricular False Tendon. Is it Associated With Innocent Murmur in Children or Heart Disease?

Cited by 7 publications

References 26 publications

Features of heritable disorders of connective tissue in children with acute rheumatic fever and rheumatic heart disease

Features of heritable disorders of connective tissue in children with acute rheumatic fever and rheumatic heart disease

Resembling Left Ventricular False Tendon in a Father and His Daughter

Cardiac ventricular false tendons: A meta‐analysis

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