Batch- and continuous propionic acid production from glycerol using free and immobilized cells of Propionibacterium acidipropionici

Abstract

Please cite this article as: Dishisha, T., Alvarez, M.T., Hatti-Kaul, R., Batch-and continuous propionic acid production from glycerol using free and immobilized cells of Propionibacterium acidipropionici, Bioresource Technology (2012), doi: http://dx.doi.org/10. 1016/j.biortech.2012.05.079 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Succinic acid-producing biofilms of Actinobacillus succinogenes: reproducibility, stability and productivity

“…Superior results were obtained with Poraver® porous glass beads (Dagher et al 2010;Dishisha et al 2012), Vukopor® and polyurethane foam (Casali et al 2012). …”

An economical biorefinery process for propionic acid production from glycerol and potato juice using high cell density fermentation

“…Retaining high cell density within the bioreactor by cell immobilization led to enhanced volumetric productivity (Dishisha et al, 2012), however the complexity of controlling such reactors in large scale due to cell growth and pH variation, limits their application for industrial production. The development of highcell-density fermentation and cell separation techniques has resulted in significant progress in fermentation technology.…”

Development of a Propionibacterium-Escherichia coli Shuttle Vector for Metabolic Engineering of Propionibacterium jensenii, an Efficient Producer of Propionic Acid

“…The reported species used for PA production include P. freudenreichii (6), P. acidipropionici (5,(7)(8)(9)(10)(11)(12)(13)(14), and P. thoenii (15). Among those, P. acidipropionici is the main producer of PA, with a maximal yield of 97 g/liter from a 3-month fed-batch culture of a PA-tolerant P. acidipropionici mutant in a fibrous bed bioreactor (31).…”

“…Due to exhaustion of petroleum resources and the serious environmental pollution caused by the utilization of fossil resources, the production of PA by microbial fermentation from renewable resources has attracted increasing attention (5). To date, the species used for PA production have included Propionibacterium freudenreichii (6), P. acidipropionici (5,(7)(8)(9)(10)(11)(12)(13)(14), and P. thoenii (15). Almost all the reports on this topic mainly focused on the optimization of the process (6-8, 11, 14, 16) and helped to significantly improve the PA production levels.…”