Batch Preparation and Characterization of Electrospun Porous Polylactic Acid-Based Nanofiber Membranes for Antibacterial Wound Dressing

Yin, Jing; Xu, Lan; Ahmed, Adnan

doi:10.1007/s42765-022-00141-y

Cited by 87 publications

(43 citation statements)

References 54 publications

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“…For example, porous PCL fibers were electrospun from a PCL/CF/DMSO solution [ 67 ]. In order to produce porous PLA nanofibers, a number of solvent/nonsolvent systems have been used, including dichloromethane (DCM)/hexane [ 68 ], DCM/DMF [ 69 ], DCM/DMAC [ 70 , 71 ], DCM/butanol [ 72 ], and CF/DMF [ 73 ]. In electrospun PVDF nanofibers, DMF/acetone solutions could be used to create porous fibers [ 74 ].…”

Section: Polymers In Electrospun Porous Fibersmentioning

confidence: 99%

“…This intriguing study expanded the potential use of porous nanofiber membranes as a novel material for wound healing. Yin et al [ 73 ] added chitosan (CS) and aloin into a polylactic acid (PLA) solution and successfully prepared batch of porous PLA/CS/aloin nanofibers (PCA) for wound dressing using a self-made electrospinning device ( Figure 11 c). The introduction of CS and aloin improved the hydrophobic property of PCL ( Figure 11 d), which might lessen the dressing’s adherence to the wound and avoid harm from dressing removal.…”

Section: Applications Of Electrospun Porous Nanofibersmentioning

confidence: 99%

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Recent Progress of the Preparation and Application of Electrospun Porous Nanofibers

Wang

Cao

et al. 2023

Polymers

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Electrospun porous nanofibers have gained a lot of interest recently in various fields because of their adjustable porous structure, high specific surface area, and large number of active sites, which can further enhance the performance of materials. This paper provides an overview of the common polymers, preparation, and applications of electrospun porous nanofibers. Firstly, the polymers commonly used to construct porous structures and the main pore-forming methods in porous nanofibers by electrospinning, namely the template method and phase separation method, are introduced. Secondly, recent applications of electrospun porous nanofibers in air purification, water treatment, energy storage, biomedicine, food packaging, sensor, sound and wave absorption, flame retardant, and heat insulation are reviewed. Finally, the challenges and possible research directions for the future study of electrospun porous nanofibers are discussed.

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Section: Polymers In Electrospun Porous Fibersmentioning

confidence: 99%

Section: Applications Of Electrospun Porous Nanofibersmentioning

confidence: 99%

Recent Progress of the Preparation and Application of Electrospun Porous Nanofibers

Wang

Cao

et al. 2023

Polymers

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“…It is a carbohydrate polymer (glycosaminoglycan) produced by the alkaline heterogeneous deacetylation of natural chitin. The content of N-acetylamino and d-glucosamine depends on the degree of deacetylation, and they are the main components of dermal tissue [205]. CS has been widely used in biomedical applications due to its high absorption, cost-effectiveness, biodegradability, immunostimulatory properties, non-toxicity, antibacterial, anti-inflammatory and remodeling behavior.…”

Section: Polysaccharides Animal Polysaccharidementioning

confidence: 99%

Recent Progress of Electrospun Herbal Medicine Nanofibers

et al. 2023

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Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed.

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“…Thanks to the high porosity of the EFs, NFMs exhibited good swelling and mechanical properties. [ 103 ]…”

Section: Structure Of Efsmentioning

confidence: 99%

A Review: Current Status and Emerging Developments on Natural Polymer‐Based Electrospun Fibers

Han

Wang

et al. 2022

Macromol. Rapid Commun.

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In recent years, natural polymer‐based electrospun fibers (EFs) with huge specific surface area, good biocompatibility, and biological activity obtained from electrospinning process exhibit tremendous vitality in the field of biomedical areas. Herein, the parameters of electrospinning from two perspectives, polymer solution such as solvent, polymeric relative molecular mass, concentration, viscosity, and conductivity of the solution, and electrospinning process such as spinning voltage, spinning flow rate, needle tip to collector distance, temperature, and humidity are first detailed. Next, the raw materials consisting of polysaccharides such as cellulose, hyaluronic acid, alginate, and chitosan as well as proteins such as collagen, gelatin, silk fibroin, and keratin are summarized. The preparation method and related characteristics of EFs with multistage structures such as porous, core–shell, Janus, bamboo‐like and other structures are introduced. The biomedical applications of these natural polymer‐based EFs mainly including tissue engineering, drug sustained release, wound dressings, and biomedical sensors are systematically recapitulated. Finally, the outlook on natural EFs is further proposed.

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Batch Preparation and Characterization of Electrospun Porous Polylactic Acid-Based Nanofiber Membranes for Antibacterial Wound Dressing

Cited by 87 publications

References 54 publications

Recent Progress of the Preparation and Application of Electrospun Porous Nanofibers

Recent Progress of the Preparation and Application of Electrospun Porous Nanofibers

Recent Progress of Electrospun Herbal Medicine Nanofibers

A Review: Current Status and Emerging Developments on Natural Polymer‐Based Electrospun Fibers

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