2021
DOI: 10.3390/vetsci8110246
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Bayesian Estimation of Diagnostic Accuracy of Three Diagnostic Tests for Bovine Tuberculosis in Egyptian Dairy Cattle Using Latent Class Models

Abstract: The aim of the present study was to calculate the sensitivity (Se) and specificity (Sp) of the single cervical tuberculin test (SCT), rapid lateral flow test (RLFT), and real-time polymerase chain reaction (RT-PCR) for the diagnosis of Mycobacterium bovis (M. bovis) infection in Egyptian dairy cattle herds within a Bayesian framework. The true M. bovis infection within-herd prevalence was assessed as a secondary objective. Data on the test results of SCT, RLFT, and RT-PCR for the detection of M. bovis were ava… Show more

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Cited by 2 publications
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“…The Walter-Hui latent class model provides a theoretical framework to address this problem, allowing the sensitivity and speci city of a set of competing diagnostic tests to be estimated when samples are available from at least two populations with differing prevalence [9,10]. In recent years this approach has been used to evaluate the relative performance of bTB diagnostics using eld data from Ireland, Spain, France, Northern Ireland, Brazil, Pakistan and Egypt [11][12][13][14][15][16][17][18][19][20]. However, only one of these studies included buffalo (and did not evaluate the WOAH recommended tuberculin test) and no systematic performance of bTB diagnostics has previously been carried out in India [18].…”
Section: Introductionmentioning
confidence: 99%
“…The Walter-Hui latent class model provides a theoretical framework to address this problem, allowing the sensitivity and speci city of a set of competing diagnostic tests to be estimated when samples are available from at least two populations with differing prevalence [9,10]. In recent years this approach has been used to evaluate the relative performance of bTB diagnostics using eld data from Ireland, Spain, France, Northern Ireland, Brazil, Pakistan and Egypt [11][12][13][14][15][16][17][18][19][20]. However, only one of these studies included buffalo (and did not evaluate the WOAH recommended tuberculin test) and no systematic performance of bTB diagnostics has previously been carried out in India [18].…”
Section: Introductionmentioning
confidence: 99%