Beer consumption reduces cerebral oxidation caused by aluminum toxicity by normalizing gene expression of tumor necrotic factor alpha and several antioxidant enzymes

Anti-Aging Effects of Monomethylsilanetriol and Maltodextrin-Stabilized Orthosilicic Acid on Nails, Skin and Hair

“…On the contrary, aluminum reduction was actually correlated directly to the consumption of M-OSA and MMST. This effect is in accordance with the literature: epidemiological studies already suggested that silicon can prevent the absorption of aluminum and/or increase its excretion [31][32][33][34]. Indeed, in nature, silicon readily forms complexes with aluminum and therefore, aluminosilicates are the most prevalent form of silicates [3].…”

Silicic Acid and Beer Consumption Reverses the Metal Imbalance and the Prooxidant Status Induced by Aluminum Nitrate in Mouse Brain

“…Therefore, the Si could somehow mitigate the damage induced by Al, restoring Zn homeostasis in the brain. These results are correlated with increased expression of Cu/Zn SOD observed after administration of the beer or silicon aluminum intoxicated rats [5]. As for Cu, it found significant positive correlations between brain Zn levels and gene expression of Cu,Zn-SOD.…”

“…Therefore, Si in the form of silicic acid may lower Al bioavailability, and hence should be considered an element that may protect against Al toxicity in the brain. In addition, our group has also demonstrated that the ingestion of Si as silicic acid or beer prevented lipid oxidation and pro-inflammatory effects induced by Al exposition [5] reverting the decline of mRNA expression of several endogenous antioxidant enzymes. Thus, keeping in mind all these results present paper hypothesized that Al administration negatively affects brain level of various metals, some of them involved in antioxidant/pro-oxidant reactions; thus, causing oxidative stress and inflammatory deleterious effects.…”

“…There is evidence that the exposure to Al causes an increase in both oxidative stress and inflammatory events [5].…”

Assessment of Potential Abatement provided by <i>Annona Muricata</i> (Prickly Custard Apple Leave) on the Toxic Effects of Aluminium Chloride on Albino Rats

“…The ubiquity of numerous aluminium compounds in the soil, water and air ensure that we live in an aluminium-rich environment (Nayak, 2002;Molley et al, 2007). Due to its abundance, every organism contains small of the tissues of mammals, including the blood, brain, liver, lung, kidney, heart and bones (Golub et al, 2000;Gonzalez et al, 2007).Over time, aluminium-contaminated water and other liquids percolate through landfills; the percolating liquid often reacts with the solid waste in the landfill, and may pose public and environmental health risks because of the contaminants it absorbs; Drinking water provide about 1% of the normal daily aluminium intake (Yokel et al, 2002).There is little doubt that in the experimental setting, aluminium is toxic to hundreds of cellular processes both in man and animals (Exley and Korchazhkina, (2001). Aluminium intoxication has been reported to cause oxidative stress and a decrease in the intracellular levels of glutathione (Gonzalez et al, 2007).…”