2021
DOI: 10.1002/fsn3.2577
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Beetroot as a functional food with huge health benefits: Antioxidant, antitumor, physical function, and chronic metabolomics activity

Abstract: Nowadays, a large number of consumers have a strong preference for the "functional foods" for the improvement of their eating diet and maintenance of their health (Jeffery, 2005;Shashirekha et al., 2015).Accordingly, fruits and vegetables are important parts of the healthy diet with the capacity of preventing several diseases (Jeffery, 2005;Shashirekha et al., 2015). In recent years, the beetroot (Beta vulgaris L.) has become popular as a potential "functional food" within this context (Frank et al., 2005). In… Show more

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Cited by 57 publications
(35 citation statements)
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“…The diversity of compounds identified in the BPFw and the different anticancer mechanisms reported for these compounds suggest that the death of breast cancer cells observed in our cell assays could be due to a synergism of these compounds, possibly acting via different pathways in a complementary way, amplifying the cytotoxic effect on the cell types studied. This synergism has previously been evidenced by the reported chemo-sensitization promoted by betacyanins in the anticancer activity of vitexin and doxorubicin in different cancer models [ 71 ]. Considering that vitexin was identified in the BPFw and that beetroot is a natural source of betacyanins, it is suggested that the synergistic effect of these molecules occurred in the BPFw.…”
Section: Resultsmentioning
confidence: 58%
“…The diversity of compounds identified in the BPFw and the different anticancer mechanisms reported for these compounds suggest that the death of breast cancer cells observed in our cell assays could be due to a synergism of these compounds, possibly acting via different pathways in a complementary way, amplifying the cytotoxic effect on the cell types studied. This synergism has previously been evidenced by the reported chemo-sensitization promoted by betacyanins in the anticancer activity of vitexin and doxorubicin in different cancer models [ 71 ]. Considering that vitexin was identified in the BPFw and that beetroot is a natural source of betacyanins, it is suggested that the synergistic effect of these molecules occurred in the BPFw.…”
Section: Resultsmentioning
confidence: 58%
“…Nutritionally, beetroot is a food source rich in proteins, carbohydrates, amino acids, phytosterols, vitamins and minerals, fibers, as well as nitrates. It also contains many phytochemicals such as polyphenols, flavonoids, betalains: betacyanins and betaxanthins [9].…”
Section: Beetrootmentioning
confidence: 99%
“…Betanin present in the root extract has been found to possess antioxidant activity that is 10 times higher than in tocopherol and three times higher than in catechin [2]. Chen et al [7] reported that betalains minimize oxidative and nitrative stress by scavenging DPPH, preventing DNA deterioration, and lowering LDL. Nitrate in beetroots lowers blood lipids, glucose, and hypertension in various chronic conditions, enhances athletic performance, and reduces muscle soreness.…”
Section: Beetrootmentioning
confidence: 99%