Behandlungserfolg bei stationären Patienten in diakonischen Epilepsiezentren

May, Theodor W.; Pfäfflin, Margarete; Brückner, Sabine; Lutz, M.; Schade, Bernd; Coban, I.; Faulmüller, A.

doi:10.1007/s10309-014-0388-9

Cited by 10 publications

(9 citation statements)

References 20 publications

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“…A majority of these patients also exhibits psychiatric comorbidities, which could compromise quality of life and treatment response [13]. As a secondary analysis of data gained in a broader epilepsy center evaluation survey [14], the present study examined the interrelationships between depressive or anxiety symptoms and seizure frequency before and after inpatient treatment. Given the recent discussion on reproducibility difficulties in science [15,16], we wanted to re-examine and extend the results of Thapar et al [10] in a sample of epilepsy inpatients.…”

Section: Aim Of This Studymentioning

confidence: 99%

“…The underlying evaluation survey was carried out as a prospective, multicenter, pre-post-design study [14]. Patients were asked to complete a questionnaire, send by mail, before admission to the center (T1, pre-measurement) and also 6 months after discharge (T2, follow-up).…”

Section: Study Design and Proceduresmentioning

confidence: 99%

“…For instance, we did not consider possible effects of the AED treatment. However, results of the underlying survey [14] have shown that the number of different seizures types and of AEDs at admission are predictors of clinically relevant seizure reduction. Future studies should also explore the treatment duration as a possible influential factor on the interaction of seizure related and psychological treatment outcomes.…”

Section: Limitationsmentioning

confidence: 99%

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Relationships of depression and anxiety symptoms with seizure frequency: Results from a multicenter follow-up study

Dehn

Pfäfflin²,

Brückner

et al. 2017

Seizure

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Section: Aim Of This Studymentioning

confidence: 99%

Section: Study Design and Proceduresmentioning

confidence: 99%

Section: Limitationsmentioning

confidence: 99%

See 1 more Smart Citation

Relationships of depression and anxiety symptoms with seizure frequency: Results from a multicenter follow-up study

Dehn

Pfäfflin²,

Brückner

et al. 2017

Seizure

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show abstract

“…With respect to their employment status, patients were categorized as “employed” (employee, self‐employed), “in education” (in [vocational] education, student), or “not employed” (sheltered work, unemployed, housewife/houseman, retirement). The subscale restrictions of everyday life of the PESOS 21,23 was presented for patients' subjective evaluation of restrictions due to their epilepsy in various aspects of everyday life, for example, mobility, education, finances, or relationships. Higher scores (range = 0–100) represent higher perceived restrictions.…”

Section: Methodsmentioning

confidence: 99%

“…25 Anxiety symptoms were measured by the Generalized Anxiety Disorder seven-item scale. 26 Perceived epilepsy-related stigma was measured by the corresponding scale of the PESOS 23 indicating patients' perception of other persons' reactions or feelings regarding their epilepsy. Higher values (range = 0-100) represent higher stigma.…”

Section: Psychological Variablesmentioning

confidence: 99%

How patients' psycho‐social profiles contribute to decision‐making in epilepsy surgery: A prospective study

et al. 2023

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Objective Identifying factors associated with surgical decision‐making is important to understand reasons for underutilization of epilepsy surgery. Neurologists' recommendations for surgery and patients' acceptance of these recommendations depend on clinical epilepsy variables, for example, lateralization and localization of seizure onset zones. Moreover, previous research shows associations with demographic factors, for example, age and sex. Here, we investigate the relevance of patients' psycho‐social profile for surgical decision‐making. Methods We prospectively studied 296 patients from two large German epilepsy centers. Multiple logistic regression analyses were used to investigate variables linked to neurologists' recommendations for and patients' acceptance of surgery or intracranial video‐electroencephalographic monitoring. Patients' psycho‐social profiles were assessed via self‐reports and controlled for various clinical–demographic variables. Model selection was performed using the Akaike information criterion. Results As expected, models for neurologists' surgery recommendations primarily revealed clinical factors such as lateralization and localization of the seizure onset zone, load with antiseizure medication (ASM), and site of the epilepsy‐center. For this outcome, employment was the only relevant psycho‐social aspect (odds ratio [OR] = .38, 95% confidence interval [CI] = .13–1.11). In contrast, three of the five relevant predictors for patients' acceptance were psycho‐social. Higher odds were found for those with more subjective ASM adverse events (OR = 1.04, 95% CI = .99–1.00), more subjective seizure severity (OR = 1.12, 95% CI = 1.01–1.24), and lower subjective cognitive impairment (OR = .98, 95% CI = .96–1.00). Significance We demonstrated the relevance of the patients' psycho‐social profile for decision‐making in epilepsy surgery, particularly for patients' decisions. Thus, in addition to clinical–demographic variables, patients' individual psycho‐social characteristics add to the understanding of surgical decision‐making. From a clinical perspective, this calls for individually tailored counseling to assist patients in finding the optimal treatment option.

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