Behavioral and Healthcare-Associated Risk Factors for Chronic Hepatitis C Virus Infection in Korea

Kim, Jong Yeop; Cho, Juhee; Hwang, Sung Ho; Kil, Ho; Bae, Si Hyun; Kim, Young Seok; Lee, Han Chu; Jeong, Sook‐Hyang

doi:10.3346/jkms.2012.27.11.1371

Cited by 18 publications

(16 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, 56·1% of patients positive for anti-HCV had detectable HCV RNA. Another study of 207 patients with chronic HCV infection 69 showed that risk factors for HCV infection include older age, needlestick injury, dental procedures, multiple sex partners (≥4), receiving a blood transfusion before 1991, and surgery.…”

Section: The Lancet Gastroenterology and Hepatology Commissionmentioning

confidence: 99%

Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission

Sarin

Kumar

Eslam

et al. 2020

The Lancet Gastroenterology & Hepatology

411

303

View full text Add to dashboard Cite

The Asia-Pacific region is home to more than half of the global population and accounted for 62·6% of global deaths due to liver diseases in 2015. 54·3% of global deaths due to cirrhosis, 72·7% of global deaths due to hepatocellular carcinoma, and more than two-thirds of the global burden of acute viral hepatitis occurred in this region in 2015. Chronic hepatitis B virus (HBV) infection caused more than half of the deaths due to cirrhosis in the region, followed by alcohol consumption (20·8%), non-alcoholic fatty liver disease (NAFLD; 12·1%), and chronic infection with hepatitis C virus (HCV; 15·7%). In 2015, HBV accounted for about half the cases of hepatocellular carcinoma in the region. Preventive strategies for viral hepatitis-related liver disease include increasing access to clean drinking water and sanitation. HBV vaccination programmes for neonates have been implemented by all countries, although birthdose coverage is extremely suboptimal in some. Availability of screening tests for blood and tissue, donor recall policies, and harm reduction strategies are in their initial stages in most countries. Many governments have put HBV and HCV drugs on their essential medicines lists and the availability of generic versions of these drugs has reduced costs. Efforts to eliminate viral hepatitis as a public health threat, together with the rapid increase in per-capita alcohol consumption in countries and the epidemic of obesity, are expected to change the spectrum of liver diseases in the Asia-Pacific region in the near future. The increasing burden of alcohol-related liver diseases can be contained through government policies to limit consumption and promote less harmful patterns of alcohol use, which are in place in some countries but need to be enforced more strictly. Steps are needed to control obesity and NAFLD, including policies to promote healthy lifestyles and regulate the food industry. Inadequate infrastructure and insufficient health-care personnel trained in liver diseases are issues that also need to be addressed in the Asia-Pacific region. The policy response of most governments to liver diseases has thus far been inadequate and poorly funded. There must be a renewed focus on prevention, early detection, timely referral, and research into the best means to introduce and improve health interventions to reduce the burden of liver diseases in the Asia-Pacific region. 168 www.thelancet.com/gastrohep Vol 5 February 2020The Lancet Gastroenterology & Hepatology Commission accounted for 108 276 (8·2%) of the total liver-related deaths in the region in 2015, compared with 929 (1·2%) of 72 437 in the USA and 4032 (0·3%) of 197 179 in Europe. Deaths in the Asia-Pacific region represented three-quarters of the global total number of deaths due to acute viral hepatitis. In 2015, the region accounted for three-quarters of the global total number of deaths related to acute HBV, almost two-thirds of those due to acute hepatitis A infection, and almost 80% of those due to acute hepatitis E infection. Of all deaths du...

show abstract

Section: The Lancet Gastroenterology and Hepatology Commissionmentioning

confidence: 99%

Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission

Sarin

Kumar

Eslam

et al. 2020

The Lancet Gastroenterology & Hepatology

411

303

View full text Add to dashboard Cite

show abstract

“…Potential risk factors for HCV transmission in Korea includes blood transfusion before HCV screening, intravenous drug use, hemodialysis, needle stick injury, tattooing, dental procedures, and multiple sexual partners. 5 , 6 …”

Section: Discussionmentioning

confidence: 99%

“…The risk factors for HCV infection in South Korea includes transfusion before 1995, intravenous drug use, multiple sex partners, hemodialysis, needle stick injury, and tattooing. 5 , 6 Interestingly, even in the South Korea, there was significant difference in HCV prevalence among the geographic regions, showing characteristically high prevalence in southern coastal area of Jeonman, Gyeonman and Busan. 7 , 8 However, the cause of geographic difference of HCV prevalence in Korea is unclear.…”

Section: Introductionmentioning

confidence: 99%

Geographic differences in the epidemiological features of HCV infection in Korea

et al. 2014

Self Cite

View full text Add to dashboard Cite

Background/AimsThe prevalence of hepatitis C virus (HCV) infection in Korea exhibits significant geographic variation, with it being higher in Busan and Jeonam than in other areas. The reason for this intranational geographic difference was investigated in this study by conducting a comparative analysis of the risk factors related to HCV infection among three geographic areas: the capital (Seoul), Busan, and the province of Jeolla.MethodsIn total, 990 patients with chronic HCV infection were prospectively enrolled at 5 university hospitals located in Seoul (n=374), Busan (n=264), and Jeolla (n=352). A standardized questionnaire survey on the risk factors for HCV infection was administered to these three groups of patients, and a comparative analysis of the findings was performed.ResultsThe analysis revealed significant regional differences in exposure to the risk factors of HCV infection. By comparison with patients in Seoul as a control group in the multivariate analysis, patients in Busan had significantly more experience of invasive medical procedures, acupuncture, cosmetic procedures, and multiple sex partners. In contrast, patients in Jeolla were significantly older, and they had a higher prevalence of hepatocellular carcinoma, a lower prevalence of multiple sex partners, and had experienced fewer invasive procedures.ConclusionsThere was a significant geographic difference in the exposure to potential risk factors of HCV infection between patients from the three studied regions. This may explain the regional variation of the prevalence of HCV infection in Korea, and should be taken into account when planning strategies for the prevention and management of HCV infection.

show abstract

“…Previous dental procedures and working abroad in neigbouring countries seem to play a role in this difference [14]. In a study related to healthcare associated risk factors for Chronic Hepatitis C infection in Korea it was observed that having multiple sex partners play a minor role in transmission [15]. In our study dental treatment, hospitalization, blood transfusion and history of operation were major risk factors in both regions but intravenous drug abuse were surprisingly a more important risk factor with a statistically significant difference in this eastern city of Turkey which prompted us to understand and explain the differences in terms of regions.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Risk Factors Frequencies of Hepatitis C in Two Provinces

Dagli¹

2016

J Infect Dis Preve Med

View full text Add to dashboard Cite

Risk factors for transmission routes of hepatitis C virus (HCV) may vary in countries like Turkey which has geographical, cultural and socioeconomical differences among regions. In this study data from two provinces of Turkey were analysed to evaluate and compare the risk factors frequencies of HCV. From 2007 through 2014, a total of anti-HCV positive 90 patients from Bursa Yuksek Ihtisas Research and Training Hospital located in the west region of Turkey and 100 patients from Kilis State Hospital located in the south east part were included in the study to compare risk factors of HCV infection. Patients were questioned about history of dental treatment, hospitalization, blood transfusion, surgical operation and intravenous drug use which are major risk factors for transmission of HCV. Overall history of previous dental treatment was the most prevalent risk factor in both provinces followed by hospitalization, blood transfusion and operation. The use of intravenous drugs was higher in Kilis with a statistically significant difference. In every patient at least one risk factor was present. Although Kilis has a conservative community and lower socio economical level, this unexpected observation may be related to reflections of border trade of drugs on society. Thus preventive measures should be taken, considering socioeconomical differences among regions.

show abstract

Behavioral and Healthcare-Associated Risk Factors for Chronic Hepatitis C Virus Infection in Korea

Cited by 18 publications

References 33 publications

Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission

Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission

Geographic differences in the epidemiological features of HCV infection in Korea

Comparison of Risk Factors Frequencies of Hepatitis C in Two Provinces

Contact Info

Product

Resources

About