SUMMARY It was shown in a prior study that mildly hypertensive patients performed significantly less effectively on several sensory-perceptual, cognitive, and psychomotor tests than did matched normotensive controls. To determine whether these deficits are attributable to elevated blood pressure per se, hypertensive and control subjects were recalled for reexamination 15 months after the original tests. Results indicated that those hypertensives in whom blood pressure had been lowered with antihypertensive drugs showed significant restoration of performance scores toward the levels of normotensive subjects. Hypertensives who had not received active treatment remained deficient as compared with controls. These results indicated that behavioral deficits in mild hypertension may be reversible consequences of the effects of elevated blood pressure on the central nervous system. (Hypertension 6: 202-208, 1984) KEY WORDS • mild hypertension • effect of treatment • behavioral consequences psychological tests E SSENTIAL hypertension has been a disease of special interest to behavioral scientists for many years. Franz Alexander, 1 in his classic psychoanalytic study of hypertension, discussed the hostility/dependency conflicts that seemed to be involved in the etiology of high blood pressure. Over the past 40 years and persisting today, there have been many studies in both animals and humans directed at clarifying psychological factors that may eventuate in elevated blood pressure. Despite this research effort, the mechanisms by which personality and environmental variables are translated into chronic, fixed hypertensive disease remain unclear, as do their implications for prevention and treatment.2 "
5The role of psychological factors in the etiology of hypertension, while capturing most of the research endeavor, has not been the only interest of investigators. Over the years a smattering of reports has suggested that high blood pressure may produce some