Behavioral Evaluation of Alzheimer Disease in Clinical Trials: Development of the Japanese Version of the GBS Scale

Homma, Akira; Niina, Rie; Ishii, Tetsuro; Hasegawa, Kanae

doi:10.1097/00002093-199100051-00008

Cited by 15 publications

(9 citation statements)

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“…The 4 areas are composed of a total of 26 items, with higher scores meaning progression of the symptoms of dementia and exacerbation of its psychological aspects and emotional aspects. The reliability and validity of the Japanese version were verified by Homma et al [18] on 246 elderly subjects with dementia. The scale allows evaluation according to total scores or scores on the individual sub-itemsj however, since there were high correlations between the total scores and the sub-item scores in this study and the purpose was to evaluate mental status in terms of sub-items, only the subscale items were used in the analysis.…”

Section: Methodsmentioning

confidence: 97%

Study on factors associated with changes in quality of life of demented elderly persons in group homes

Funaki

Kaneko

Okamura

2005

Scandinavian Journal of Occupational Therapy

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The purpose of the present study was to attempt to identify changes in quality of life (QOL) and factors associated with them shortly after demented elderly residents entered a group home. The subjects were 25 demented elderly persons who had entered a group home within the previous 3 months. Their QOL and factors associated with it were evaluated on two occasions, at baseline and 3 months later. An objective scale for dementia, the Quality of Life Questionnaire for Dementia (QOL-D), was used to evaluate their QOL. The results showed a significant change between the QOL-D scores at baseline and 3 months later, and changes in housekeeping item scores were extracted as factors associated with changes in QOL-D. These findings suggest that the QOL score rises soon after entering a group home, and that the acquisition of roles within the group home may influence the increase in QOL.

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Section: Methodsmentioning

confidence: 97%

Study on factors associated with changes in quality of life of demented elderly persons in group homes

Funaki

Kaneko

Okamura

2005

Scandinavian Journal of Occupational Therapy

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“…The GBSS-J scale (the Japanese version of the Gottfries, Brane, Steen (GBS) Scale) 21 was used to determine the effect of medical treatment because this test is currently used in the evaluation of pateints with AD. The GBSS-J consists of five items: GBSS-J-A (cognitive function), GBSS-J-B (spontaneity), GBSS-J-C (feeling function), GBSS-J-D (other moral condition), and GBSS-J-E (movement function).…”

Section: Methodsmentioning

confidence: 99%

Effect of aromatherapy on patients with Alzheimer's disease

Jimbo

Kimura²,

Taniguchi³

et al. 2009

Psychogeriatrics

195

159

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Objective: Recently, the importance of non-pharmacological therapies for dementia has come to the fore. In the present study, we examined the curative effects of aromatherpay in dementia in 28 elderly people, 17 of whom had Alzheimer's disease (AD). Methods: After a control period of 28 days, aromatherapy was performed over the following 28 days, with a wash out period of another 28 days. Aromatherapy consisted of the use of rosemary and lemon essential oils in the morning, and lavender and orange in the evening. To determine the effects of aromatherpay, patients were evaluated using the Japanese version of the Gottfries, Brane, Steen scale (GBSS-J), Functional Assessment Staging of Alzheimer's disease (FAST), a revised version of Hasegawa's Dementia Scale (HDS-R), and the Touch Panel-type Dementia Assessment Scale (TDAS) four times: before the control period, after the control period, after aromatherpay, and after the washout period. Results: All patients showed significant improvement in personal orientation related to cognitive function on both the GBSS-J and TDAS after therapy. In particular, patients with AD showed significant improvement in total TDAS scores. Result of routine laboratory tests showed no significant changes, suggesting that there were no side-effects associated with the use of aromatherapy. Results from Zarit's score showed no significant changes, suggesting that caregivers had no effect on the improved patient scores seen in the other tests. Conclusions:In conclusion, we found aromatherapy an efficacious nonpharmacological therapy for dementia. Aromatherapy may have some potential for improving cognitive function, especially in AD patients.

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“…None employed QL as a primary outcome measure. Four other studies mentioned the term 'quality of life', in reference to changes in cognitive behaviour which can determine the QL of demented patients and their quality of daily living [10][11][12][13]. Several studies em ployed Instrumental Activities of Daily Living (IADL) [10,13] and Activities of Daily Living (ADL) and Physi cal Self-Maintenance Scale (PSMS) [ 13] measures without describing them as QL indices.…”

Section: Resultsmentioning

confidence: 99%

Quality of Life in Alzheimer’s Disease

Howard

Rockwood²

1995

Dement Geriatr Cogn Disord

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We reviewed and independently ranked the measurement properties of quality of life (QL) instruments currently used in antidementia drug trials for Alzheimer''s disease. Of 36 read reports, 5 measured and 4 mentioned QL. Eight instruments, labelled QL measures, included questionnaires measuring function, self-rating instruments measuring the caregivers'' impression of the impact of sickness and deterioration of memory, and observational rating scales measuring function. The most thoroughly tested QL measure was the Progressive Deterioration Scale. The instruments with the most promising measurement properties were the Progressive Deterioration Scale and the Italian Quality of Life Scale. Most instruments now used to assess QL in anti-dementia drug trials have not been adequately validated in patients with Alzheimer''s disease. Effort should be directed both to conceptual and practical development in the assessment of QL in dementia.

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Behavioral Evaluation of Alzheimer Disease in Clinical Trials: Development of the Japanese Version of the GBS Scale

Cited by 15 publications

References 0 publications

Study on factors associated with changes in quality of life of demented elderly persons in group homes

Study on factors associated with changes in quality of life of demented elderly persons in group homes

Effect of aromatherapy on patients with Alzheimer's disease

Quality of Life in Alzheimer’s Disease

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