A B S T R A C TThe study explored the impact of personality traits, perceived risk, and perceived uncertainty on investment performance of individual investors trading on the Vietnam stock market. The study conducted in-depth interviews, a pilot study, and a survey distributed to 430 individual investors. Results showed that Conscientiousness and perceived uncertainty directly affected investment performance. Openness, Extraversion, and Neuroticism indirectly influenced investment performance through the mediation of perceived uncertainty. This study suggested that individual investors should perceive uncertain situations when they invest in securities. Especially, investors who are prone to Openness, Extraversion, and Neuroticism must pay attention to uncertainty before they make investing decisions. Since Agreeableness did not affect investment performance, those who are dominant to this trait should have prudent considerations for equity investment decisions.