Behavioral pharmacology of central nervous system stimulants

Ja, Harvey

doi:10.1016/0028-3908(87)90066-9

Cited by 26 publications

(5 citation statements)

References 11 publications

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“…Although there is a well-established literature showing that d-amphetamine increases performance on computerized tasks of performance and attention (Weiss and Laties 1962;Gunne 1977;Spiegel 1979;Harvey 1987;Johnson et al 1996), presumably due to enhancement of catecholamine Robbins 1987, 1992) and particularly dopamine (DA) release (Drachman 1977), there is a paucity of information on the effects of methamphetamine on cognition in drug-naive subjects (Johnson et al 2000;McTavish et al 2001). The extant literature has focused on trying to determine whether chronic methamphetamine users, compared with healthy individuals, experience a deterioration in cognitive function (Salo et al 2002), rather than enhanced cognition, presumably as a result of frontostriatal damage (Ernst et al 2000;Volkow et al 2001).…”

Section: Introductionmentioning

confidence: 98%

Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition

et al. 2004

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Section: Introductionmentioning

confidence: 98%

Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition

et al. 2004

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“…Yet, while ample studies have demonstrated that d-amphetamine enhances cognitive processing on computerized tasks that test performance and attention (Gunne, 1977;Harvey, 1987;Johnson et al, 1996;Spiegel, 1979;Weiss and Laties, 1962), presumably due to enhancement of catecholamine Robbins, 1987, 1992) and particularly dopamine release (Drachman, 1977), only one study has reported on the effects of intravenously administered methamphetamine on cognitive performance in methamphetamine-dependent individuals (Johnson et al, 2005b). In that study, intravenous dmethamphetamine produced dose-dependent increases in attention, concentration, and psychomotor performance.…”

Section: Introductionmentioning

confidence: 99%

Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individuals

Johnson

Roache

Ait-Daoud

et al. 2007

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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Methamphetamine-dependent individuals often cite the need to maintain enhanced cognitive performance and attention as a reason for continuing or relapsing to drug-taking. Further, methamphetamine addicts might not comply with taking a potentially therapeutic medication if it had a profound effect on these cognitive processes. Topiramate, a sulfamate-substituted fructopyranose derivative, has been suggested as a putative therapeutic medication for treating methamphetamine dependence. Examination of topiramate's effects on cognitive performance and attention is a clinically and scientifically important component of understanding its potential therapeutic profile. In 10 male and female individuals who met DSM-IV criteria for methamphetamine dependence, we examined the effects of low (50 mg b.i.d.)-and high (100 mg b.i.d.)-dose topiramate -in both the presence and absence of low (15 mg)-and high (30 mg)-dose intravenous methamphetamine -on cognitive performance, attention, and concentration on the rapid visual information processing task and the digit symbol substitution test. Intravenous methamphetamine enhanced cognitive performance, attention, and concentration among recently withdrawn methamphetamine addicts -an effect that hitherto had not been well characterized. Topiramate's cognitive effects were mixed and rather paradoxical, with a tendency to improve attention and concentration both alone and in the presence of methamphetamine while worsening psychomotor retardation. No deleterious interaction occurred between topiramate and methamphetamine on any of these cognitive processes. While clinical studies with topiramate should Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. NIH Public Access

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“…D-methamphetamine increases achievement on computerized tasks of performance and attention (Harvey 1987;Spiegel 1979) by enhancing catecholamine Robbins 1987, 1992) (especially DA) release (Drachman 1977). Dihydropyridine-class calcium channel antagonists (DCCCA) may improve learning and performance in animals (Quevedo et al 1998).…”

mentioning

confidence: 99%

Effects of Isradipine, a Dihydropyridine-Class Calcium Channel Antagonist, on D-Methamphetamine-Induced Cognitive and Physiological Changes in Humans

Johnson

Ait-Daoud

Wells

2000

Neuropsychopharmacology

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Behavioral pharmacology of central nervous system stimulants

Cited by 26 publications

References 11 publications

Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition

Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition

Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individuals

Effects of Isradipine, a Dihydropyridine-Class Calcium Channel Antagonist, on D-Methamphetamine-Induced Cognitive and Physiological Changes in Humans

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