Behavioral toxicology: A new agenda for assessing the risks of environmental pollution.

Weiss, Bernard

doi:10.1037/10114-005

Cited by 5 publications

(8 citation statements)

References 54 publications

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“…Some of the problems in prescribing exposure standards legitimately follow from methodological limitations. Establishing causal relationships between exposure to environmental chemicals and manifestations of disabilities in humans is a challenging task, particularly when the exposures occur at relatively low doses (Nadakavukaren, 2000;Schettler et al, 2000;Weiss, 1992Weiss, , 1997.…”

Section: Establishing Cause and Effect: A Research Nightmarementioning

confidence: 99%

“…Clinical and neuropsychologists as well as psychiatrists are increasingly called to testify in toxic tort cases. Cognitive psychologists interested in risk assessment have investigated the factors that have an impact on decision making (e.g., Slovic, 2000), and they could contribute to the discussion of conceptualizing risk differently as applied to impacts on child development (Goldman & Koduru, 2000;Landrigan et al, 2004;Weiss, 1992).…”

Section: The Potential For Psychologistsmentioning

confidence: 99%

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Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

Koger¹,

Schettler²,

Weiss³

2005

American Psychologist

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Developmental, learning, and behavioral disabilities are a significant public health problem. Environmental chemicals can interfere with brain development during critical periods, thereby impacting sensory, motor, and cognitive function. Because regulation in the United States is based on limited testing protocols and essentially requires proof of harm rather than proof of lack of harm, some undefined fraction of these disabilities may reflect adverse impacts of this "vast toxicological experiment" (H. L. Needleman, as quoted in B. Weiss & P. J. Landrigan, 2000, p. 373). Yet the hazards of environmental pollutants are inherently preventable. Psychologists can help prevent developmental disabilities by mobilizing and affecting public policy, educating and informing consumers, contributing to interdisciplinary research efforts, and taking action within their own homes and communities to reduce the toxic threat to children.

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Section: Establishing Cause and Effect: A Research Nightmarementioning

confidence: 99%

Section: The Potential For Psychologistsmentioning

confidence: 99%

Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

Koger¹,

Schettler²,

Weiss³

2005

American Psychologist

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“…The trick is to find a differentiated subset and show their dynamic interactions with other biological and environmental variables over time, perhaps the life span. For instance, Weiss (14) notes that there are some neurotoxins that appear to accelerate the aging process. Bellinger (15), in an excellent commentary on interpreting the literature on lead and child development, chides researchers for "neglecting the role of the experimental system" when comparing and reconciling disparate findings.…”

Section: Importance Of Definitions and Theories Of Mrdd To Neurotoxicologymentioning

confidence: 99%

“…Breese et al (18) hypothesized that neonatal depletion of dopamine receptors is responsible for the distinctive phenotype of self-biting exhibited by most Lesch-Nyhan cases. It appears that the combination of a genetic susceptibility, abnormal brain development, and environmental reinforcement combines at about the age of [6][7][8][9][10][11][12][13][14][15][16][17][18] months to develop this intransigent selfbiting for which there is no satisfactory intervention to date.…”

Section: Genetic Conditons and Mrddmentioning

confidence: 99%

Mental retardation and developmental disabilities influenced by environmental neurotoxic insults.

Schroeder

2000

Environ Health Perspect

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This paper sets a framework for the discussion of neurotoxicity as a potentially major contributor to the etiology of many types of mental retardation and developmental disabilities. In the past the literatures on developmental neurotoxicology and on mental retardation have evolved independently, yet we know that the developing brain is a target for neurotoxicity in the developing central nervous system through many stages of pregnancy as well as during infancy and early childhood. Our definitions and theories of mental retardation and developmental disabilities affect the models of neurotoxicity we espouse. For instance, models of developmental risk in neurotoxicology have guided environmental regulation to reduce the likelihood of neurotoxic effects. On the other hand, models of developmental risk for mental retardation aim not only at primary prevention,but also at secondary and tertiary prevention through early intervention. In the future, dynamic models of neuroplasticity based on the study of gene-brain-behavior relationships are likely to guide our views of developmental neurotoxicology and prevention of mental retardation and other disabilities.

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“…The task is to find an optimum set of measures that reveal how the system functions as a whole with a view to understanding the underlying mechanisms. Although there are currently several variations of theories of intelligence relevant to MR, e.g., Sternberg (11), Ceci (12), and Gardner (13) (14) notes that there are some neurotoxins that appear to accelerate the aging process. Bellinger (15), in an excellent commentary on interpreting the literature on lead and child development, chides researchers for "neglecting the role of the experimental system" when comparing and reconciling disparate findings.…”

mentioning

confidence: 99%

Mental Retardation and Developmental Disabilities Influenced by Environmental Neurotoxic Insults

Schroeder¹

2000

Environmental Health Perspectives

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Behavioral toxicology: A new agenda for assessing the risks of environmental pollution.

Cited by 5 publications

References 54 publications

Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

Environmental Toxicants and Developmental Disabilities: A Challenge for Psychologists.

Mental retardation and developmental disabilities influenced by environmental neurotoxic insults.

Mental Retardation and Developmental Disabilities Influenced by Environmental Neurotoxic Insults

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