The purpose of this study is to explore cases of missing persons suspected of being criminal. Specifically, this research aims to empirically describe the circumstances surrounding criminal disappearances and examine whether there are different subcategories within these cases using a victimological framework. The data used in this study come from an operational police database. The sample includes 155 unsolved missing person cases whose thorough investigation by the police concluded that a criminal motive remained the most likely hypothesis. These cases occurred on the entire territory of metropolitan France and overseas. Multidimensional scale analysis was used to explore the context of disappearance according to missing person characteristics, lifestyle, everyday activities, and situational exposure at the time of the disappearance. Results show that the distribution of variables in a two-dimensional space reveals four distinct different categories related to lifestyle and situational exposure: riskier lifestyle, riskier situation, safer situation, and safer lifestyle. This study is the first to empirically explore unsolved missing person cases suspected of a criminal outcome. Moreover, the framework used in this study demonstrates the importance of victimology in an investigative context.