Infectious mononucleosis is a clinical syndrome characterized by fever, lymphadenopathy and
pharyngitis. Neurologic complications of infectious mononucleosis, such as the development of
Guillain-Barre syndrome, have been rarely reported and usually present late in the course of
the disease. We describe a case of a 29 year old male with no significant past medical history who
was diagnosed with Guillain-Barre syndrome following an infection with Epstein-Barr
virus associated infectious mononucleosis. Supportive treatment resulted in full recovery.