2012
DOI: 10.1186/cc11356
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Bench to bedside review: Extracorporeal carbon dioxide removal, past present and future

Abstract: Acute respiratory distress syndrome (ARDS) has a substantial mortality rate and annually affects more than 140,000 people in the USA alone. Standard management includes lung protective ventilation but this impairs carbon dioxide clearance and may lead to right heart dysfunction or increased intracranial pressure. Extracorporeal carbon dioxide removal has the potential to optimize lung protective ventilation by uncoupling oxygenation and carbon dioxide clearance. The aim of this article is to review the carbon … Show more

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Cited by 109 publications
(104 citation statements)
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“…The use of extracorporeal carbon dioxide removal devices may be beneficial in this scenario. 40 Positioning the patient in a head-up position may help with both ventilation and reducing ICP.…”
Section: Pulmonarymentioning
confidence: 99%
“…The use of extracorporeal carbon dioxide removal devices may be beneficial in this scenario. 40 Positioning the patient in a head-up position may help with both ventilation and reducing ICP.…”
Section: Pulmonarymentioning
confidence: 99%
“…In conclusion, experience with ECMO has been 43 Karakurt et [36][37][38][39][40][41][42][43][44][45][46][47][48] improving with better survival rates and decreasing morbidity. Considering ECMO for patients with respiratory failure or heart failure when conventional therapies failed, if the underlying pathology is reversible or as a bridge to heart and/or lung transplantation is important.…”
Section: Prognosismentioning
confidence: 99%
“…If the patient has sufficient arterial pressure (arteriovenous pressure gradient ≥ 60 mm Hg), a pumpless system may be used in ECCOR. Otherwise, we have to use mechanical pump [42].…”
Section: Extra Corporeal Membrane Oxygenation (Ecmo) and Extra Corpormentioning
confidence: 99%
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“…Positive pressure ventilation improves oxygenation and CO2 removal by alveolar recruitment, increasing alveolar volume and redistribution of extracellular lung water. So it is reasonable to implement positive pressure ventilation in patients on high O2 like this level [6].…”
Section: Nimv Vs High-flow Oxygen Therapy (Hfot)mentioning
confidence: 99%