Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial

Madjd, Ameneh; Taylor, Moira A.; Delavari, Alireza; Malekzadeh, Reza; Macdonald, I. A.; Farshchi, Hamid R

doi:10.3945/ajcn.116.134163

Cited by 47 publications

(73 citation statements)

References 36 publications

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“…Six trials (27,(29)(30)(31)(32)(33) out of eight trials showed that reducing evening intake produced greater weight loss than reducing breakfast intake or eating three meals throughout the day. In one study (27) , this was only true for severely obese participants (>170 % RBW) and there was no difference in treatment arms for moderately obese participants (<170 % RBW).…”

Section: Synthesis Of Results For Clinical Trialsmentioning

confidence: 99%

“…Keim et al (31) observed similar results whereby participants in the 'breakfast group' (35 % TDEI at breakfast and 30 % TDEI at and after dinner) lost significantly more weight than those in the 'dinner group' (30 % TDEI at breakfast and 70 % TDEI at and after dinner) (P < 0•01) after 6 weeks. Lombardo et al (32) and Madjd et al (33) observed that participants in the 'breakfast group' lost significantly more weight than those in the 'dinner Conversely, Sensi et al (34) and Del Ponte et al (28) found that a single meal of 2860 kJ produced greater weight loss when consumed for 18 d at 18.00 hours compared with 10.00 hours. However, no statistical test of significance was performed in either trial, making it difficult to assess the significance of the results.…”

Section: Synthesis Of Results For Clinical Trialsmentioning

confidence: 99%

“…Eight clinical trials (27)(28)(29)(30)(31)(32)(33)(34) with sample size ranging from 10 193 participants (mean = 62) were included in the review. Four trials (30)(31)(32)(33) included women only and one trial (34) did not specify the sex of participants. All other studies included both males and females, with the percentage of female participants ranging from 60 to 90 %.…”

Section: Study Characteristics Of Clinical Trialsmentioning

confidence: 99%

“…The majority of interventions manipulated the distribution of TDEI so that a greater proportion was either consumed at the breakfast or dinner meal (29)(30)(31)(32)(33) . Two trials compared single meals consumed during the day or in the evening (28,34) , and another trial (27) included a third group who consumed daily energy intake at three meals throughout the day.…”

Section: Intervention Characteristics Of Clinical Trialsmentioning

confidence: 99%

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Are large dinners associated with excess weight, and does eating a smaller dinner achieve greater weight loss? A systematic review and meta-analysis

2017

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There are suggestions that large evening meals are associated with greater BMI. This study reviewed systematically the association between evening energy intake and weight in adults and aimed to determine whether reducing evening intake achieves weight loss. Databases searched were MEDLINE, PubMed, Cinahl, Web of Science, Cochrane Library of Clinical Trials, EMBASE and SCOPUS. Eligible observational studies investigated the relationship between BMI and evening energy intake. Eligible intervention trials compared weight change between groups where the proportion of evening intake was manipulated. Evening intake was defined as energy consumed during a certain time - for example 18.00-21.00 hours - or self-defined meal slots - that is 'dinner'. The search yielded 121 full texts that were reviewed for eligibility by two independent reviewers. In all, ten observational studies and eight clinical trials were included in the systematic review with four and five included in the meta-analyses, respectively. Four observational studies showed a positive association between large evening intake and BMI, five showed no association and one showed an inverse relationship. The meta-analysis of observational studies showed a non-significant trend between BMI and evening intake (P=0·06). The meta-analysis of intervention trials showed no difference in weight change between small and large dinner groups (-0·89 kg; 95 % CI -2·52, 0·75, P=0·29). This analysis was limited by significant heterogeneity, and many trials had an unknown or high risk of bias. Recommendations to reduce evening intake for weight loss cannot be substantiated by clinical evidence, and more well-controlled intervention trials are needed.

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Section: Synthesis Of Results For Clinical Trialsmentioning

confidence: 99%

Section: Synthesis Of Results For Clinical Trialsmentioning

confidence: 99%

Section: Study Characteristics Of Clinical Trialsmentioning

confidence: 99%

Section: Intervention Characteristics Of Clinical Trialsmentioning

confidence: 99%

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Are large dinners associated with excess weight, and does eating a smaller dinner achieve greater weight loss? A systematic review and meta-analysis

2017

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“…ADA guidelines, for example [15], recommend individualizing meal plans using the DASH diet [10], mediterranean diet [9], low fat diet, vegetarian/vegan diet [11,12], low carbohydrate diet [4][5][6][7][8] or diabetes plate method [15]. On the other hand, several studies have also shown the importance of meal timing in improving glycaemia [16][17][18][19][20][21][22][23], but they are not yet in the guidelines. Translational efforts in this area are exceedingly slow.…”

Section: Introductionmentioning

confidence: 99%

Obvious impairment of attention and processing speed in patients with schizoaffective disorder

Chen¹,

Chen²,

Chong³

et al. 2016

Neuropsychiatry

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A physician with a 19-year history of type 2 diabetes and impaired awareness of hypoglycemia sought to lower the hypoglycemia risk using continuous glucose monitoring to optimize the medications-meals-exercise triad. As part of the lifestyle modification the patient found distributing daily carbohydrate consumption skewed toward the morning, when physical activity is relatively high, lowered glycemic variability. She also found that the second meal could be the biggest meal of the day.

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Meal Timing and Anthropometric and Metabolic Outcomes

Liu,

Eso,

Cook

et al. 2024

JAMA Netw Open

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ImportanceMeal timing strategies, such as time-restricted eating (TRE), reducing meal frequency, or altering calorie distribution across the day, have gained interest for their potential to enhance weight loss and metabolic health, particularly in managing chronic diseases, yet their long-term benefits are not known.ObjectiveTo evaluate the association between meal timing strategies (≥12 weeks) and anthropometric and metabolic indicators.Data SourcesMedline, Embase, CINAHL, and Cochrane CENTRAL were searched from inception to October 17, 2023.Study SelectionRandomized clinical trials, regardless of language and publication date, involving adults 18 years and older, evaluating within-day meal timing patterns for 12 or more weeks, and reporting anthropometric measures were included. Studies were excluded if participants had eating disorders, prior significant weight change, underwent bariatric surgery, were pregnant, or if controlled variables differed between groups.Data Extraction and SynthesisStudy quality was determined via Risk of Bias 2.0 tool. Data were extracted independently by multiple reviewers. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were used. Meta-analysis was performed using random-effects model on pooled continuous outcomes with 2 or more studies.Main Outcome and MeasuresWeight change in kilograms, reported as between-group mean difference with 95% CIs.ResultsSixty-nine reports of 29 randomized clinical trials including 2485 individuals (1703 [69%] female; mean [SD] age, 44 [9.5] years; and mean [SD] body mass index, 33 [3.5]) were included. Study interventions included TRE (17 studies), meal frequency (8 studies), and calorie distribution (4 studies). There were some concerns of risk of bias for 7 studies and high concerns for 22 studies. Statistically significant weight change was observed in TRE when compared with control (–1.37 kg; 95% CI, –1.99 to –0.75 kg). Lower meal frequency and earlier caloric distribution were also both associated with greater change (–1.85 kg; 95% CI, –3.55 to –0.13 kg; and –1.75 kg; 95% CI, –2.37 to –1.13 kg, respectively).Conclusions and RelevanceThe findings of this meta-analysis suggest that TRE, lower meal frequency, and earlier caloric distribution in the day may reduce weight compared with standard care and/or nutritional advice; however, the effect sizes found were small and of uncertain clinical importance. High heterogeneity and risk of bias among included studies led to concerns about the certainty of the underpinning evidence. Further research, including trials with larger sample sizes, standardized interventions with prescribed or matched energy intake, and longer follow-up, are needed.

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Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial

Cited by 47 publications

References 36 publications

Are large dinners associated with excess weight, and does eating a smaller dinner achieve greater weight loss? A systematic review and meta-analysis

Are large dinners associated with excess weight, and does eating a smaller dinner achieve greater weight loss? A systematic review and meta-analysis

Obvious impairment of attention and processing speed in patients with schizoaffective disorder

Meal Timing and Anthropometric and Metabolic Outcomes

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