Beneficial Effects of Baduanjin Exercise on Left Ventricular Remodelling in Patients after Acute Myocardial Infarction: an Exploratory Clinical Trial and Proteomic Analysis

Mao, Shuai; Zhang, Xiaoxuan; Chen, Minggui; Wang, Chuyang; Chen, Qubo; Guo, Liheng; Zhang, Minzhou; Hinek, Aleksander

doi:10.1007/s10557-020-07047-0

Cited by 19 publications

(22 citation statements)

References 44 publications

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“…The sample sizes in the reports ranged from 1 to 271, and the median was 68 (interquartile range 42–110). Most of the studies were conducted in China, including ten in Fujian [ 20 – 29 ], six in Beijing [ 19 , 30 – 34 ], five in Taiwan [ 35 – 39 ], five in Guangdong [ 7 , 40 – 43 ], four in Hong Kong [ 6 , 44 – 46 ], three in Shanghai [ 18 , 47 , 48 ], two in each of Hebei [ 49 , 50 ], Jiangsu [ 51 , 52 ], Sichuan [ 53 , 54 ], and Hubei [ 17 , 55 ], and one in each of Tianjin [ 4 ], Shanxi [ 56 ], Jiangxi [ 57 ], and Macau [ 58 ]. One study was conducted in Singapore [ 59 ], and one study was conducted in the USA [ 60 ].…”

Section: Resultsmentioning

confidence: 99%

“…Of the 47 eligible studies, 8 evidently did not include controls [ 7 , 28 , 38 , 39 , 48 , 58 – 60 ], and 5 used more than two control groups [ 21 – 24 , 49 ]. Three studies used walking as a control [ 34 , 42 , 54 ], and other control measures used in single studies were muscle relaxation training [ 30 ], reading [ 6 ], physical therapy [ 19 ], and an aerobic exercise [ 43 ]. Twenty-seven studies used non-interventional controls, including usual care [ 4 , 17 , 18 , 20 , 25 – 27 , 29 , 31 – 33 , 35 – 37 , 40 , 41 , 44 – 47 , 50 – 53 , 55 – 57 ].…”

Section: Resultsmentioning

confidence: 99%

“…Of the 47 studies assessed, 22 reported protocols used to monitor AEs [ 4 , 6 , 17 , 20 , 21 , 26 , 27 , 29 , 32 , 35 , 37 , 38 , 40 , 41 , 43 , 44 , 46 – 48 , 52 , 55 , 59 ], but only 2 reported the actual occurrence of AEs during the trial [ 44 , 52 ]. Of these two studies, one reported muscle ache only [ 52 ] and the other reported muscle ache, palpitation, giddiness, knee pain, backache, fatigue, nervousness, dizziness, shoulder pain, chest tightness, and shortness of breath [ 44 ] ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

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The Safety of Baduanjin Exercise: A Systematic Review

Fang

Zhang

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Objectives. Baduanjin exercise is a form of Qigong exercise therapy that has become increasingly popular worldwide. The aims of the current systematic review were to summarize reported adverse events potentially associated with Baduanjin exercise based on currently available literature and to evaluate the quality of the methods used to monitor adverse events in the trials assessed. Methods. The English databases PubMed, Cochrane library, and EMbase were searched from inception to October 2020 using the keywords “Baduanjin” or “eight session brocade.” Only studies that included Baduanjin exercise therapy were included. Results. Forty-seven trials with a total of 3877 participants were included in this systematic review. Twenty-two studies reported protocols for monitoring adverse events, and two studies reported the occurrence of adverse events during training. The adverse events reported included palpitation, giddiness, knee pain, backache, fatigue, nervousness, dizziness, shoulder pain, chest tightness, shortness of breath, and muscle ache. Conclusions. Only two studies reported adverse events that were potentially caused by Baduanjin exercise. Adverse events related to Baduanjin exercise in patients with chronic fatigue syndrome may include muscle ache, palpitation, giddiness, knee pain, backache, fatigue, nervousness, dizziness, shoulder pain, chest tightness, and shortness of breath. Further studies conducted in accordance with the Consolidated Standards of Reporting Trials statement guideline incorporating monitoring of adverse events are recommended. Additional clinical trials in which Baduanjin exercise is used as a main intervention are needed, and further meta-analysis may be required to assess its safety and reach more informed conclusions in this regard in the future.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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The Safety of Baduanjin Exercise: A Systematic Review

Fang

Zhang

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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“…[ 7 ] Modern clinical practice has proved that Baduanjin plays a therapeutic and rehabilitative role in hypertension, chronic obstructive pulmonary disease (COPD), chronic heart failure, myocardial infarction and etc. [ 8 – 11 ] Baduanjin does not require the use of equipment, and will not be restricted because of the site. It is a long-term, low-intensity aerobic exercise.…”

Section: Introductionmentioning

confidence: 99%

Effects of Baduanjin on glucose and lipid metabolism in diabetic patients

Gao

et al. 2021

Medicine

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Background: Baduanjin is an ancient technique of physical and breathing exercises (Dao Yin). This technique is divided into eight sections and each section is a motion, so it is called “Baduanjin”. It is practice without equipment, simple and easy to learn, whose effect is significant leading to good fitness effect. Diabetes mellitus is a chronic metabolic disease. Clinical studies have reported that Baduanjin can affect the metabolism of blood glucose and blood lipid in diabetic patients, but the reported efficacy is different among different studies. Therefore, the study is aimed to systematically evaluate the size and differences of the impact of Baduanjin on the metabolism of glucose and lipid in diabetic patients. Methods: Retrieved randomized controlled trials(RCTs) on effects of Baduanjin on glucose and lipid metabolism in diabetic patients from PubMed, Web of Science, the Cochrane Library, Embase, CNKI with computer while mutually retrieved the same things from Chinese Clinical Trial Registry(ChiCTR), Google Academic and Baidu Academic. The retrieval time was from their establishment to October 2020. Then 2 researchers independently extracted relevant data and evaluated the quality of the included literatures, and meta-analysis was conducted on the included literatures using RevMan5.3. Results: This research used outcome indicators like fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, total cholesterol content and triglyceride content to explore the effect of Baduanjin on glucose and lipid metabolism in diabetic patients specifically. Conclusion: The research will provide reliable evidence-based proof for Baduanjin improving glucose and lipid metabolism of diabetic patients. Ethics and dissemination: Private information from individuals will not be published. This systematic review also does not involve endangering participant rights. Ethical approval was not required. The results may be published in a peer-reviewed journal or disseminated at relevant conferences. OSF Registration number: DOI 10.17605/ OSF.IO/AGJHQ.

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“…More and more studies have found that combining with Baduanjin exercise can signi cantly improve the prognosis of clinical chronic diseases [24]. In the study of Ye et al, it was found that Baduanjin exercise improves the balance and quality of life of the elderly with chronic diseases [25], and that Baduanjin promotes the rehabilitation of patients with cardiovascular diseases [26]. It is worth noting that these studies on Baduanjin are mainly elderly participants or the recovery period of cardiovascular events caused by hypertension.…”

Section: Discussionmentioning

confidence: 99%

Effects of Baduanjin on Essential Hypertension: A Study Protocol for a Randomized Controlled Trial

Guan

Yang

Guan

et al. 2021

Preprint

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Background: Clinical treatment of hypertension recommends the use of drugs to reduce the incidence and mortality of cardiovascular diseases in hypertensive patients. However, the side effects of long-term medication and economic pressure have increased the medical community's interest in Baduanjin as a method of exercise therapy. Clinical studies have shown that Baduanjin can be used to treat various diseases, and it can also regulate physical and mental factors such as tension and anxiety. This study aims to evaluate the antihypertensive effect of Baduanjin on patients with essential hypertension. Methods/design: In this study, 92 patients with essential hypertension were randomly divided into the Baduanjin group and the routine care group, using a randomized, active control, evaluator blind method, and two parallel control methods, with 46 cases in each group, signed informed Subjects with the consent form will manage their blood pressure by limiting salt intake, losing weight, drinking moderately, exercising, and adjusting dietary intake during the first visit. In addition to self-management, the Baduanjin group will also conduct 30-minute Baduanjin training three times a week for a total of 8 weeks. The main result is the measurement of blood pressure. In addition, body composition will be measured as a secondary result.Discussion: This study is a randomized controlled Baduanjin trial and is not currently widely used. It may provide valuable data on the impact of Baduanjin on essential hypertension, which will inform non-drug treatment options for this disease.Trial registration: Chinese Clinical Trial Registration Center, ChiCTR200003570. Register on August 16, 2020.

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Beneficial Effects of Baduanjin Exercise on Left Ventricular Remodelling in Patients after Acute Myocardial Infarction: an Exploratory Clinical Trial and Proteomic Analysis

Cited by 19 publications

References 44 publications

The Safety of Baduanjin Exercise: A Systematic Review

The Safety of Baduanjin Exercise: A Systematic Review

Effects of Baduanjin on glucose and lipid metabolism in diabetic patients

Effects of Baduanjin on Essential Hypertension: A Study Protocol for a Randomized Controlled Trial

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