Beneficial Effects of Marine Algal Compounds in Cosmeceuticals

Abstract

The name “cosmeceuticals” is derived from “cosmetics and pharmaceuticals”, indicating that a specific product contains active ingredients. Marine algae have gained much importance in cosmeceutical product development due to their rich bioactive compounds. In the present review, marine algal compounds (phlorotannins, sulfated polysaccharides and tyrosinase inhibitors) have been discussed toward cosmeceutical application. In addition, atopic dermatitis and the possible role of matrix metalloproteinase (MMP) in skin-related diseases have been explored extensively for cosmeceutical products. The proper development of marine algae compounds will be helpful in cosmeceutical product development and in the development of the cosmeceutical industry.

Potential of antioxidant extracts produced by aqueous processing of renewable resources for the formulation of cosmetics

“…Phlorotannins are phenolic compounds exclusive of marine seaweeds, but these organisms, particularly brown algae, also contain a variety of components with antioxidant action (such as polyunsaturated fatty acids, proteins, pigments, vitamins, polysaccharides and carotenoids). The phlorotannins and algal polysaccharides exhibit anticoagulant, antiviral, antioxidative, anticancer, antiinflammatory and immunomodulatory actions, and could have potential for the development of nutraceutical, pharmaceutical and cosmeceutical products (Batista González et al, 2009;Balboa et al, 2013;Thomas and Kim, 2013). Valorization and utilization of the constituents of the brown macroalga Sargassum muticum was proposed, since the solvent extracts (Kim et al, 2007) and the soluble fractions obtained after autohydrolysis (González-López et al, 2012) were active in vitro antioxidants.…”

Algae as Nutrition, Medicine and Cosmetic: The Forgotten History, Present Status and Future Trends

“…Eckol and phlorofucofuroeckol-A α 2-plasmin inhibitor Anticoagulant [27] Sulphated fucan -------Anticoagulant [26] Dieckol Inhibitory effect on hyaluronidase Antiallergic [32] Ecklonia maxima Eckol and phloroglucinol α-glucosidase inhibitor Antidiabetic [27] Ecklonia stolonifera…”

“…Against photo aging of skin [32] Eckol HIV-1 reverse transcriptase inhibitor Anti-AIDs [27] 6,6′-bieckol Inhibitory effect on histamine release Antiallergic [32] α-amylase and α-glucosidase inhibitor Antidiabetic [27] HIV-1 reverse transcriptase inhibitor Anti-AIDs [27] Fucodiphlorethol-G Free radical scavenger (DPPH assay) Antioxidant [28] α-amylase and α-glucosidase inhibitor Antidiabetic [27] 8,4‖-bieckol and 8,8'-bieckol HIV-1 reverse transcriptase inhibitor Anti-AIDs [28] Dieckol, phlorofucofuroeckol A, eckol, eckstolonol and Angiotensin converting enzyme inhibitor Antihypertensive [27] World Journal of Pharmacy and Pharmaceutical Sciences triphlorethol…”

“…Against photo aging of skin [32] Eckstolonol and phlorotannin, DEPP radical-scavenging activity Antioxidant [28] Eckol, phlorofucofuroeckol-A and dieckol…”

Marine Polysaccharides as Multifunctional Pharmaceutical Excipients

“…Tablet disintegrant usually considered as the rate determining step (RDS) in a faster drug release. Marine polysaccharides may behave as a good disintegrating agent by increasing the porosity, wetability and wicking or capillary action and operate by swelling in the presence of aqueous luids in tablet formulations to facilitate the breakdown of the tablet into granules upon entry into the stomach [7] (Figure 3). …”