Benefits of Coffee Consumption for Human Health: An Overview

Abstract

Background: Coffee is one of the most consumed beverages worldwide and is popular for its characteristic flavor and rich organoleptic properties. Aim: Based on published articles, the aims of this review are i) study the association between coffee consumption and benefits to human health; ii) the effects of coffee consumption on some pathologies; and iii) provide a description of coffee’s bioactive compounds. Discussion: Coffee presents bioactive compounds, which include phenolic compounds, especially chlorogenic acid (caffeoylquinic acid), trigonelline, and diterpenes, such as cafestol and kahweol. These compounds are related to the beneficial effects for human health, including high antioxidant activity, antimutagenic activity, hepatoprotective action, reduced incidence of type 2 diabetes mellitus, reduced risk of cardiovascular diseases, decreased incidence of inflammatory diseases, reduced menopausal symptoms, and others. Coffee’s bioactive compounds are caffeine, chlorogenic acid, trigonelline, cafestol and kahweol, which are closely related to coffee’s beneficial effects. Conclusion: The present review clarified that the benefits of moderate coffee consumption outweigh the associated risks.

Beyond Conventional Treatment: Exploring Natural Therapies for Paracetamol Overdose

“…Coffee is a member of the Rubiaceae family, and the genus Coffea is typically grown in subtropical and tropical climates, with 90 to 124 species (35) . Coffee is one of the most consumed beverages worldwide and is popular for its characteristic flavor and rich organoleptic properties (36) . Coffee contains protein, carbohydrates, lipids, and minerals in addition to other bioactive components including caffeine, nicotinic acid, chlorogenic acids, diterpenes, trigonelline formic acid, and acetic acid (37) .…”

“…These compounds have beneficial effects on human health, including high antioxidant, antiinflammatory, antimutagenic, and antidiabetic activity, and hepatoprotective cardiovascular protective activity (36) . Studies reported that coffee can attenuate paracetamol toxicity by downregulating lipid peroxidation, and CYP2E1 gene expression, and increasing GSH (38,39) .…”