Benign Effusions

Firat, Pınar

doi:10.1007/978-3-319-76478-8_1

Cited by 2 publications

(2 citation statements)

References 82 publications

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“…The serous pleural cavity is an enclosed space covered by the parietal and visceral layers of serous membranes, which are lined by a monolayer of mesothelial cells supported on fibrous tissue rich in capillaries and lymphatics. Under physiological conditions, these two layers are in juxtaposition and only a small amount of fluid is present inside these compartments, acting as a lubricant to avoid friction . Accumulation of abnormal quantities of pleural fluid (effusions) occurs for various reasons, from inflammatory to neoplastic conditions, and cytopathological examination of these specimens is a fast and minimally invasive method for prompt verification of the presence of neoplastic cells and possible use of ancillary studies such as immunohistochemistry and molecular biology.…”

Section: Introductionmentioning

confidence: 99%

A 2‐year retrospective study on pleural effusions: A cancer centre experience

et al. 2019

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Background Cytopathological examination of pleural effusions is a fast and minimally invasive method for verification of the presence of neoplastic cells. We report our 2‐year experience using a categorised diagnostic system and reporting risks of malignancy (ROMs) for each defined category. Methods Cytological reports of patients between November 2016 and October 2018 were collected, with results primarily classified into a five‐tiered classification scheme. Immunohistochemistry markers used in cytology and their results were also recorded. Final agreement to histology and overall test performance was calculated for cases with available concomitant (up to 3 months) pleural biopsies. Results A total of 519 samples from 385 patients were collected, being 29 (5.6%) classified as non‐diagnostic, 291 (56%) as negative, 28 (5.4%) as atypical, 30 (5.8%) as suspicious and 141 (27.2%) as positive. Most requested markers were calretinin, TTF1, Ber‐EP4 and Gata‐3, being conclusive in 45 (76.3%) cases. Total cyto‐histological agreement was achieved in 49 (80.3%) specimens, with an overall sensitivity and specificity of 69.4% and 93.3%, respectively. Positive predictive value was 96.2% and negative predictive value was of 56%. ROM for each diagnostic category was 50% for non‐diagnostic, 44% for negative, 50% for atypical, 83.3% for suspicious and 96.2% for positive. Conclusions Our 2‐year retrospective study has shown a high specificity and positive predictive value for pleural cytology. The use of a five‐tiered system has also shown to be highly effective, with a concordantly progressive higher ROM for the assigned diagnostic categories.

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Section: Introductionmentioning

confidence: 99%

A 2‐year retrospective study on pleural effusions: A cancer centre experience

et al. 2019

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“…MOSFETin iletim ve yalıtım safhalarında devrede iki ayrı durum görülür. MOSFET iletimde iken giriş gerilimi primer sargısına uygulanır ve sabit bir gerilim olduğundan primer endüktansı üzerinde akım artmaya başlar [17][18]. Bu esnada sekonder sargılarından akım geçmez.…”

Section: şEkil 5 Pwm Sinyali (Pwm Signal)unclassified

Elektrikli Araç Batarya Aktif Dengeleme Sistemleri için Çift Yönlü Flyback Dönüştürücü Tasarımı

Şahin

Kilinç²

2022

Politeknik Dergisi

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Benign Effusions

Cited by 2 publications

References 82 publications

A 2‐year retrospective study on pleural effusions: A cancer centre experience

A 2‐year retrospective study on pleural effusions: A cancer centre experience

Elektrikli Araç Batarya Aktif Dengeleme Sistemleri için Çift Yönlü Flyback Dönüştürücü Tasarımı

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