Benign lesions mimicking malignant tumors of the esophagus

Wolf, Barbara C.; Khettry, Urmila; Leonardi, Howard K.; Neptune, Wilford B.; Bhattacharyya, Achyut K.; Legg, Merle A.

doi:10.1016/s0046-8177(88)80342-3

Cited by 31 publications

(18 citation statements)

References 19 publications

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“…To our knowledge, less than 30 patients with diffuse leiomyomatosis of the esophagus have been reported in the English literature [1, 2, 3, 4, 5, 6, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]. Fernandes et al [2]described a patient and reviewed 14 previous cases of diffuse leiomyomatosis of the esophagus which could be classified into two types.…”

Section: Discussionmentioning

confidence: 99%

Diffuse Leiomyomatosis of the Esophagus

Cheng¹,

Hsu²,

Hsu³

et al. 2000

Dig Surg

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Background: Leiomyomas are rare esophagus neoplasms. They are usually solitary, and the diffuse lesion is extremely rare. Case Report: A 19-year-old male presented with a 3-year history of occasional dysphagia and postprandial regurgitation. The chest radiographs showed a huge mass in the posterior mediastinum. Barium esophagograms showed narrowing of the middle third esophagus with proximal dilatation. The fibroesophagoscopy demonstrated multiple submucosal nodules below a level 22 cm from the incisor and covered with intact mucosa. CT scans of the chest showed a long segment of circumferential soft tissue in the posterior mediastinum which encircled and involved the upper two thirds of the esophagus. An intrathoracic esophagectomy with cervical esophagogastrostomy via the substernal route was performed. Grossly, multiple confluent myomatous nodules circumferentially involved the upper and middle third of the esophagus. Histologic findings showed diffuse leiomyomatosis of the esophagus. Conclusion: Esophageal leiomyomatosis should be considered in a young patient with long-standing dysphagia in whom smooth, tapered esophageal narrowing on barium study and circumferential esophageal wall thickening on CT scan are seen. An esophagectomy combined with a reconstruction procedure is indicated.

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Section: Discussionmentioning

confidence: 99%

Diffuse Leiomyomatosis of the Esophagus

Cheng¹,

Hsu²,

Hsu³

et al. 2000

Dig Surg

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“…[1][2][3]6 Only 17 cases of IFP of the esophagus have been reported (Table 1). 1,[7][8][9][10][11][12][13][14][15][16][17] In summary, the mean age of the reported patients was 51.2 years, and the male/female ratio was 12 : 5. IFP of the esophagus is most frequently found in the lower portion of the esophagus or at the esophagogastric junction.…”

Section: Discussionmentioning

confidence: 99%

“…Most esophageal polyps are fibrovascular, and an inflammatory fibroid polyp (IFP) of the esophagus is very rare. 1 IFP of the gastrointestinal tract has been described by various terms. Konjetzny, in 1920, 2 used "polypoid fibroma" for submucosal tumor of the stomach with eosinophilic infiltration, and the term "inflammatory fibroid polyp" has been widely used since the report of Helwig and Ranier 3 in 1953.…”

Section: Introductionmentioning

confidence: 99%

An inflammatory fibroid polyp of the esophagus concomitant with a superficial flat carcinoma

Morishima

Tashiro

Nitta

et al. 1999

International Journal of Clinical Oncology

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We report a rare case of an inflammatory fibroid polyp (IFP) of the esophagus associated with an extensive early mucosal carcinoma. At esophagoscopy, a polypoid lesion 2 cm in length, and a non-stained area detected by the Lugol iodine spray staining method were found in the mid-thoracic portion, and esophagectomy was performed. Endoscopic polypectomy is thought to be useful for the diagnosis of IFP, but it should be kept in mind that IFP may be concomitant with carcinoma. Indeed, in our patient, early esophageal carcinoma was discovered because of the symptoms of dysphagia induced by the IFP.

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“…Even when large, they may be missed on endoscopic examination because their surface is similar to normal oesophageal mucosa [13]. They should be differentiated from inflammatory fibroid polyps, which do rarely occur in the oesophagus and appear similar to their counterparts elsewhere in the gastrointestinal tract [14][15][16].…”

Section: Diffuse Leiomyomatosismentioning

confidence: 99%