Benzimidazole derivatives: Spectrum of pharmacological activity and toxicological properties (a review)

Crystal structure of 2-methoxy-6-(((2-(1-methyl-1H-benzo[d] imidazol-2-yl)phenyl)imino)methyl)phenol — ethanol (1/1), C24H25N3O3

“…The Schi -base compounds with benzimidazole moiety [3,4] and their metal complexes [5,6] also have been reported on their broad biological activities. The title compound is a polydentate Schi -base with benzimidazole and steric hindrance synthesized in a convenient approach.…”

“…In the crystal packing structure, there are some intermolecular forces including C-H· · · O hydrogen bonds and π-π stacking forces. The distance between the six-membered ring centroids of Cg (3) and Cg(2) (1−x, −y, 2−z) is 3.8075(12) Å.…”

Crystal structure of 1-(1H-benzimidazole)methyl-1H-benztriazole dihydrate, C14H11N5 · 2H2O

“…Benzimidazole and related heterocycle compounds have been extensively investigated because of their applications as intermediate for the synthesis of chemiluminescent compounds [2] and as cytomegalovirus inhibitors and anthelmintic agents [3]. The asymmetric unit of the title crystal structure consists of one 1-(1H-benzimidazole)methyl-1H-benzotriazole and two water molecules.…”

Mannich Bases of 2-Substituted Benzimidazoles – A Review

“…They are also reported as anthelmintic agents and in diverse human therapeutic areas such as treatment of ulcers, anti inflammatory agents and as antihistaminics (Spasov et al,1999). Benzimidazole derivatives are named as "privileged sub structures" for drug design because of their diverse uses (Evans et al, 1988;Mason et al, 1999).…”