Benzodiazepine prescribing to the Swiss adult population: results from a national survey of community pharmacies

Petitjean, Sylvie; Ladewig, D; Meier, Christoph; Amrein, R.; Wiesbeck, Gerhard A.

doi:10.1097/yic.0b013e328105e0f2

Cited by 115 publications

(100 citation statements)

References 16 publications

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“…This is in agreement with findings about the use of BDZs in various countries (Lagnaoui et al, 2004;Neutel, 2005;Petitjean et al, 2007;Hollingworth and Siskind, 2010;Holm et al, 2012;Sonnenberg et al, 2012;Cloos et al, 2015;Olfson et al, 2015), as well as Brazil (Firmino et al, 2011;Brunoni et al, 2013), and may reflect tendencies in the general use of BDZs. Contrary to our hypothesis and findings from other studies, the proportions of women among BDZ users and BDZ non-users were almost identical, and female gender did not emerge as a significant predictor of BDZ use in OCD individuals.…”

supporting

confidence: 81%

“…We also hypothesised that BDZ use was more likely in older and female patients with OCD, based on studies in various countries showing that BDZ use tends to be positively correlated with age and female gender (Lagnaoui et al, 2004;Neutel, 2005;Petitjean et al, 2007;Hollingworth and Siskind, 2010;Firmino et al, 2011;Holm et al, 2012;Sonnenberg et al, 2012;Brunoni et al, 2013;Cloos et al, 2015;Olfson et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Use of benzodiazepines in obsessive–compulsive disorder

Starčević

Berle

Rosario

et al. 2016

International Clinical Psychopharmacology

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Objectives: This study aimed to determine the frequency of benzodiazepine (BDZ) use in a large sample of patients with obsessive-compulsive disorder (OCD) and ascertain the type of BDZ used and the correlates and predictors of BDZ use in OCD. Conclusions: This is the first study to comprehensively examine BDZ use in OCD subjects, demonstrating that it is relatively common, despite recommendations from treatment guidelines. Use of BDZs in combination with several other medications over time and in patients with marked anxiety suggests that OCD patients taking BDZs may be more complex and more difficult to manage. This calls for further research and clarification of the role of BDZs in the treatment of OCD. Methods

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supporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Use of benzodiazepines in obsessive–compulsive disorder

Starčević

Berle

Rosario

et al. 2016

International Clinical Psychopharmacology

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“…For instance, it is important to say that isolated auto-medication produces harmful and undesirable consumption. These drugs, which belong to a group of small tranquilizers, due to their wide therapeutic power, are the reason for abuse and are prescribed in excess in general medical practice (2)(3) .…”

Section: Introductionmentioning

confidence: 99%

Consumption of benzodiazepines without prescription among first-year nursing students at the University of Guayaquil, school of nursing, Ecuador

Paredes

Miasso

Tirapelli

2008

Rev. Latino-Am. Enfermagem

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Pinos Paredes N, Miasso AI, Tirapelli CR. Consumption of benzodiazepines without prescription among first-year nursing students at the University of Guayaquil. Rev Latino-am Enfermagem 2008 maio-junho; 16(especial):634-9.This study aimed to determine the consumption of benzodiazepines without prescription among firstyear students from a nursing school of a public University in Ecuador. This is a descriptive, transversal and explanatory study with a quantitative approach. A questionnaire was used for data collection. The population studied was of 181 students. The results showed that 10.5% of the students had consumed benzodiazepine without prescription once in their lives. Of these, 6.1% consumed benzodiazepine in the last year, and 3.9% are currently consuming it. The diazepam was the most consumed BZD without prescription and pharmacies, were the place of higher access. The main reasons for the benzodiazepine consumption were: insomnia, anxiety, stress, depression, family and economical problems. The use of benzodiazepines with non-medicinal purposes is related to problems such as memory loss, retirement syndrome and sedation. When benzodiazepines are consumed jointly with alcohol or other drugs they can lead to coma or death. This study shows the serious consequences benzodiazepines cause when used by nursing students in Ecuador.DESCRIPTORS: auto medication; GABA-A receptors; students, nursing CONSUMO DE BENZODIACEPINAS SIN PRESCRIPCIÓN MÉDICA EN LOS/AS ESTUDIANTES DE PRIMER AÑO DE LA ESCUELA DE ENFERMERÍA DE LA UNIVERSIDAD DE GUAYAQUIL, ECUADORLa finalidad de este estudio fue determinar el consumo de benzodiacepinas sin prescripción en estudiantes del primer año de enfermería de una universidad pública de Ecuador. Se trata de un estudio transversal, descriptivo y exploratorio, con aproximación cuantitativa. Un cuestionario fue usado para la recolecta de los datos. La población estudiada fue compuesta por 181 estudiantes. Los resultados muestran que el 10,5% de los estudiantes consumió benzodiacepinas sin prescripción médica alguna vez en la vida. Del total, el 6,1% consumió en el último año y el 3,9% usan actualmente. El Diazepan fue la BZD más usada sin prescripción médica, siendo la farmacia el local de mayor acceso. Entre los principales motivos para el consumo de benzodiacepinas se encuentran: insomnio, ansiedad, estrés, depresión y problemas familiares o económicos. El uso de benzodiacepinas con propósitos no-medicinales está relacionado a problemas de pérdida de la memoria, síndrome de abstinencia y sedación. Cuando son combinados con alcohol u otras drogas, pueden llevar a la coma y a la muerte. Este estudio muestra las graves consecuencias que las benzodiacepinas pueden ocasionar cuando utilizados por estudiantes de enfermería en Ecuador. DESCRIPTORES: automedicación; receptores GABA-A; estudiantes de enfermería CONSUMO DE BENZODIAZEPINOS SEM PRESCRIÇÃO MÉDICA ENTRE ESTUDANTES DO PRIMEIRO ANO DA ESCOLA DE ENFERMAGEM DA UNIVERSIDADE DE GUAYAQUIL, EQUADORO objetivo deste estudo foi determinar o consumo...

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“…Despite the risks associated with the use of this class of drugs (falls [13], fractures, accidents at work [14][15][16][17][18][19]), the utilisation of benzodiazepines increased during the 5 years of observation, with an estimated increase of more than 400% between 2011 and 2012, an increase less pronounced in 2013 and a slight decline in 2014 and 2015 (Fig. 1).…”

Section: Discussionmentioning

confidence: 99%