Benzotriazole: A novel synthetic auxiliary

Synthesis of 1,3-diarylacetones from N-(arylacetyl)benzotriazoles via arylketene intermediates

“…Benzotriazole is a good leaving group and used extensively as a novel synthetic auxiliary [ 5,6]. For example, 1 -formylbenzotriazole is an excellent formulating reagent [7].…”

Facile Synthesis of Benzotriazines and Indoles by Ring-Scissions of α-Benzotriazol-1-yl Hydrazones

“…Removal of the solvent via rotary evaporation gave a residue which was subjected to column chromatography (hexane and ethylacetate as eluent) to give the expected products. 1,145.1,144.0,135.7,135.0,133.1,133.0,129.8,129.1,129.0,128.8,128.1,127.8,127.7,127.5,124.4,119.6,110.2,60.0,21.2. Anal.…”

Benzotriazole as a Synthetic Auxiliary

“…Since 1985, he has published more than 300 papers and several reviews dealing with benzotriazole. [5][6][7][8][9][10][11] He defined benzotriazole as a compound which fulfils all demands of an ideal synthetic auxiliary: it is inexpensive, stable, it can be introduced readily at the beginning of the reaction sequence, it is stable during various synthetic operations, it exerts an activating influence on the other parts of the molecule, it is easy to remove and can be recovered and used again. 12 Our group started with benzotriazole chemistry in 1977 and the results have been published in more than 30 papers.…”