Benzyl Alcohol: A Covert Fragrance

Jacob, Sharon E.; Barron, Gregory

doi:10.2310/6620.2007.06068

Cited by 12 publications

(5 citation statements)

References 10 publications

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“…25 In cosmetics, it can be found in moisturizers, shampoos, baby products, eye makeup removers, self-tanners, deodorants, make-up materials, and hair dyes, 26 and sometimes in products labelled "fragrance-free." 36 Chlorhexidine is used as an antiseptic, and is also found in ophthalmic products or impregnated in implantable material. It is also used as a preservative in cosmetics such as make-up remover lotions, moisturizers, baby cleansing products, hair conditioners, toothpastes, repairing balms, personal care products, and topical medications.…”

Section: Resultsmentioning

confidence: 99%

“…Benzyl alcohol is frequently used as a preservative in medicinal topicals or injectable preparations, 22,24 or as a solvent in industrial products 25 . In cosmetics, it can be found in moisturizers, shampoos, baby products, eye makeup removers, self‐tanners, deodorants, make‐up materials, and hair dyes, 26 and sometimes in products labelled “fragrance‐free.” 36 …”

Section: Discussionmentioning

confidence: 99%

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Multiple cases of sensitization to an antiseptic containing chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol with different profiles of sensitization in adults and children

et al. 2022

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Background An aqueous antiseptic containing “chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol” (CBB) is widely used in France. The only previous documented study dealing with allergic contact dermatitis (ACD) to this antiseptic is one small case series in children. The French Vigilance Network for Dermatology and Allergy (REVIDAL‐GERDA) has collected many cases in the last few years. Objectives To evaluate the clinical and sensitization profiles of patients diagnosed with ACD to CBB. Methods We performed a retrospective study of patients with contact dermatitis to CBB and positive tests to CBB and/or at least one of its components. All patients had to be tested with all components of CBB. Results A total of 102 patients (71 adults and 31 children) were included. The lesions were extensive in 63% of patients and 55% had delayed time to diagnosis. CBB patch tests were positive in 93.8% of cases. The allergen was identified in 97% of patients, mainly benzyl alcohol in adults (81.7%) and chlorhexidine digluconate in children (54.8%). About 32.4% of the patients were sensitized to several components. Conclusion CBB is a cause of ACD at all ages. The components of the antiseptic should be tested. The sensitization profile seems to be different between adults and children.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Multiple cases of sensitization to an antiseptic containing chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol with different profiles of sensitization in adults and children

et al. 2022

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“…In our analysis, benzyl alcohol was in 19% of diaper wipes and 4.9% of topical diaper preparations. 43,44 However, sensitization for benzyl alcohol is low, with a 0% RPPT rate in children younger than 5 and 0.1% in children younger than 18 years. 5 Benzoic acid is found in 3 (4.8%) of 63 disposable wipes and 2 (4.9%) of 41 topical preparations in our analysis.…”

Section: Fragrancesmentioning

confidence: 98%

Potential Allergens in Disposable Diaper Wipes, Topical Diaper Preparations, and Disposable Diapers

Yu¹,

Treat²,

Chaney³

et al. 2016

Dermatitis

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Botanical extracts, including members of the Compositae family, were the most commonly represented potential allergen in both diaper wipes and topical preparations. Other potential allergens identified with high frequency include α-tocopherol, fragrances, propylene glycol, parabens, iodopropynyl butylcarbamate, and lanolin. Frequent culprits such as formaldehyde releasers and methylchloroisothiazolinone/methylisothiazolinone were not prevalent in our analyzed products.

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“…Benzyl alcohol is an aromatic alcohol that can serve various functions in products, such as fragrance, preservative, solvent, anesthetic, and/or antipruritic, and is commonly found in topical medications 1 . Only a few cases of allergic contact dermatitis (ACD) in response to benzyl alcohol in medications have been reported 2‐6 .…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis from benzyl alcohol in hydrocortisone cream

2022

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acute generalized exanthematous pustulosis, case report, patch test, transdermal ketoprofen patch Acute generalized exanthematous pustulosis (AGEP) is considered a severe, type IVd cutaneous adverse drug reaction. 1 Ketoprofen is well known to induce photo (-aggravated) allergic contact dermatitis. 2 To the best of our knowledge, AGEP due to a transdermal ketoprofen patch has never been reported before.

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Benzyl Alcohol: A Covert Fragrance

Cited by 12 publications

References 10 publications

Multiple cases of sensitization to an antiseptic containing chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol with different profiles of sensitization in adults and children

Multiple cases of sensitization to an antiseptic containing chlorhexidine digluconate/benzalkonium chloride/benzyl alcohol with different profiles of sensitization in adults and children

Potential Allergens in Disposable Diaper Wipes, Topical Diaper Preparations, and Disposable Diapers

Allergic contact dermatitis from benzyl alcohol in hydrocortisone cream

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