Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

Chan, Joyce; Law, CK; Hamblion, Esther; Fung, Hong; Rudge, James W.

doi:10.12809/hkmj166098

Cited by 20 publications

(28 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The infection spreads among the population through direct contact with an infected individual (through oral‐pharyngeal secretions or by direct contact with blisters), or via contaminated water or objects with respiratory secretions, blister fluid, and/or feces of infected individuals …”

Section: Introductionmentioning

confidence: 99%

Hand‐foot‐and‐mouth disease in uruguay: Coxsackievirus A6 identified as causative of an outbreak in a rural childcare center

Lizasoain

Piegas

Victoria

et al. 2019

Journal of Medical Virology

View full text Add to dashboard Cite

To know the epidemiological context of hand‐foot‐and‐mouth disease (HFMD) in a region of Uruguay and to identify the Enterovirus responsible for an outbreak in a rural childcare center in 2018. Swab samples from skin lesions and/or stools samples were collected from children suffering HFMD during an outbreak in a rural childcare center. Samples were subject to viral RNA extraction and reverse‐transcription polymerase chain reaction towards VP1 coding segment, to identify the Enterovirus type by sequencing and phylogenetic analysis. Total of 149 cases of HFMD affecting 98 boys and 51 girls were reported in Salto Province‐Uruguay in 2018. Total 60% of the cases were originated from outbreaks, which occurred in ten educative and childcare institutions from both urban and rural areas. Coxsackievirus‐6 (CV‐A6) was identified as responsible for one of the rural outbreaks. Uruguayan strains were more related to strains reported in Russia, Turkey, and Germany (2014‐2017) than to strains reported in Brazil and Argentina from 2015 to 2016. This is the first report of CV‐A6‐associated HFMD in Uruguay, evidencing a wide geographic range of the virus in the Latin American region. Our report also warns about CV‐A6‐associated HFMD during winter, contrarily to most reports that register HFMD during summer and fall seasons.

show abstract

Section: Introductionmentioning

confidence: 99%

Hand‐foot‐and‐mouth disease in uruguay: Coxsackievirus A6 identified as causative of an outbreak in a rural childcare center

Lizasoain

Piegas

Victoria

et al. 2019

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…Although normally the course of the disease is not very dramatic, the morbidity and mortality associated with the recent enterovirus outbreaks has demonstrated the urgent need for effective antiviral treatment and for more education regarding the disease prophylaxis. 1,6,9 The case series in this paper has demonstrated that HFMD affects not only children or immunocompromised subjects, but in favorable conditions may easily spread to a generally healthy adult person. According to some reports, approx.…”

Section: Discussionmentioning

confidence: 85%

“…Strict implementation of basic protocols like monitoring cleanliness of the hands, utensils and drinking water, together with preventing affected children from attending school and other childcare facilities is recommended. 2,4,9 …”

Section: Discussionmentioning

confidence: 99%

“…4,6 Due to the high infectivity, the restrictive hygienic procedures in limiting interpersonal spread and isolation of symptomatic cases are essential in preventing HFMD transmission and controlling the outbreaks. 9 In this paper, we present a case of intra-familial transmission of hand, foot and mouth disease between 2 children attending kindergarten and their generally healthy adult relative in Poland. Prodromal signs, clinical presentation, diagnostics, prophylaxis, and treatment options are also discussed.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Hand, foot and mouth disease as an emerging public health problem: Case report of familial child-to-adult transmission

Ślebioda

Dorocka‐Bobkowska

2018

Dent. Med. Probl.

View full text Add to dashboard Cite

Hand, foot and mouth disease (HFMD) is a highly contagious viral infectious disease that commonly affects small children. Typical clinical symptoms include low-grade fever, malaise and myalgia followed by a characteristic maculovesicular eruption on hands, feet and the oral cavity. In most cases, the disease is self-limiting, but some severe complications, including pneumonia, meningitis and encephalitis, may occasionally occur. The most severe outbreaks of HFMD have been observed in Asia-Pacific region; however, epidemics in Europe and America have also occurred in the past. The disease is caused by an infection with various members of Picornaviridae family in the genus enterovirus, most commonly by Coxsackievirus A6 (CVA6), Coxsackievirus A16 (CVA16), and Enterovirus 71 (EV71).This report describes the intra-familial transmission of hand, foot and mouth disease between 2 sibling children (a 3-year-old girl and a 5-year-old boy) and their immunocompetent mother in Poland. Clinical presentation with signs, symptoms and a suggested treatment regime are discussed and illustrated.

show abstract

“…Pada penelitian kami, anak yang mendapatkan ASI lebih enam bulan berisiko lebih kecil dibandingkan dengan kurang dari enam bulan. 20 Lokasi lesi terbanyak adalah pada tangan, kaki, dan mulut sebesar 91%, sedangkan hanya sekitar 36% lesi menyebar keseluruh tubuh. Penyebaran lesi di seluruh tubuh terjadi pada dua anak dengan obesitas, sedangkan tiga anak gizi buruk dan satu gizi baik.…”

Section: Pembahasanunclassified

Gambaran Klinis dan Karakteristik Genetik Human Enterovirus 71 Penyebab Hand Foot and Mouth Disease di Banjarmasin – Kalimantan Selatan Tahun 2016

Hartoyo

2020

View full text Add to dashboard Cite

Latar belakang. Hand foot and mouth desease (HFMD) adalah infeksi virus akut yang biasanya menyerang anak dibawah 10 tahun, sangat menular dan dapat menimbulkan komplikasi fatal. Tujuan. Untuk mengetahui gejala klinis, komplikasi, dan serotipe penyebab HFMD di Banjarmasin. Metode. Penelitian deskriptif, sampel diambil di poliklinik RSUD Ulin dan RS. Islam Banjarmasin periode November 2015 sampai dengan Febuari 2016 yang terdiagnosis HFMD oleh dokter spesialis anak, terdapat 23 sampel. Hasil. Dari 23 pasien secara klinis HFMD terdapat 18 (78%) positif entero virus, 71, 2 (9%) positif campak, dan 3 (13%) negatif. Umur rata rata ±20,77 bulan, laki laki 12 (52%) dan perempuan 11 (48%). Gejala klinis demam 17 (74%), rash/ lesi kulit 23 (100%), susah makan 14(61%), batuk 8(35%), pilek 9(39%), diare 5(22%), konjungtivitis 2(9%), muntah 4(17%), nyeri menelan 14(61%), dan kenjang 2(9%). Kesimpulan. Penyebab HFMD terbanyak adalah EV71, umur tesering kurang dari 3 tahun, gejala klinis terbanyak lesi kulit, demam dan tidak didapatkan komplikasi serius (intakranial). Sari Pediatri 2020;21 (5):271-5 Background. Hand foot and mouth disease (HFMD) is an acute viral infection that usually attacks children under 10 years, is highly contagious and can cause fatal complications. Objective. To find out clinical symptoms, complications, and serotypes that cause HFMD in Banjarmasin. Method. Descriptive research, samples were taken at the clinic of Ulin Regional Hospital and Hospital. Islam Banjarmasin from November 2015 to February 2016 diagnosed with HFMD by pediatricians, there were 23 samples. Results. From 23 clinically HFMD sufferers there were 18 (78%) positive Entero virus 71, 2 (9%) positive for measles and 3 (13%) results were negative. Average age ± 20.77 months, men 12 (52%) and women 11 (48%). Clinical symptoms of fever 17 (74%), rash / skin lesions 23 (100%), difficulty eating 14 (61%), cough 8 (35%), colds 9 (39%), diarrhea 5 (22%), conjunctivitis 2 (9%), vomiting 4 (17%), painful swallowing 14 (61%) and 2 (9%). Conclusion. The most common cause of HFMD is EV71, the age of testing is less than 3 years, the most clinical symptoms are skin lesions, fever and no serious complications (intracranial). Sari Pediatri 2020;21(5):271-5

show abstract

Best practices to prevent transmission and control outbreaks of hand, foot, and mouth disease in childcare facilities: a systematic review

Cited by 20 publications

References 27 publications

Hand‐foot‐and‐mouth disease in uruguay: Coxsackievirus A6 identified as causative of an outbreak in a rural childcare center

Hand‐foot‐and‐mouth disease in uruguay: Coxsackievirus A6 identified as causative of an outbreak in a rural childcare center

Hand, foot and mouth disease as an emerging public health problem: Case report of familial child-to-adult transmission

Gambaran Klinis dan Karakteristik Genetik Human Enterovirus 71 Penyebab Hand Foot and Mouth Disease di Banjarmasin – Kalimantan Selatan Tahun 2016

Contact Info

Product

Resources

About