Beta-alanine supplementation enhances judo-related performance in highly-trained athletes

Kratz, Caroline; Painelli, Vítor de Salles; Nemezio, Kleiner; Silva, Rafael Pires da; Franchini, Émerson; Zagatto, Alessandro Moura; Gualano, Bruno; Artioli, Guilherme Giannini

doi:10.1016/j.jsams.2016.08.014

Cited by 50 publications

(91 citation statements)

References 31 publications

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“…Chronic β-alanine supplementation is a nutritional strategy that has been used to improve performance in some sports, especially those characterized by high intensity [10, 11, 13]. The ergogenic effect of β-alanine supplementation is related to an increase in carnosine content, which is a dipeptide that has multiple functions [33], mainly muscle buffering [2].…”

Section: Discussionmentioning

confidence: 99%

“…Although the ergogenic effects of β-alanine have been investigated in various exercise models [12], much less is known about its potential use in different sport disciplines. In this regard, studies have examined the β-alanine ergogenic potential mainly in individual sports (i.e., running [11], swimming [10], judo [13] and others). The results, however, are mixed and the performance enhancing effects seem to be related to the specificities of each sport discipline.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

et al. 2016

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The purpose of this study was to investigate the effect of four weeks of β-alanine supplementation on repeated sprint ability in water polo players. Twenty-two male water polo players participated in the study, divided randomly into two homogeneous groups (placebo and β-alanine groups). The study design was double-blind, parallel and placebo controlled. Before and after the supplementation period (28 days), the athletes performed two specific repeated sprint ability tests interspaced by a 30-minute swimming test. Participants received 4.8g∙day-1 of the supplement (dextrose or β-alanine) on the first 10 days and 6.4g∙day-1 on the final 18 days. There was no significant group-time interaction for any variable. The qualitative inference for substantial changes demonstrated a likely beneficial effect in the β-alanine group (β-alanine vs placebo) for mean time (6.6±0.4s vs 6.7±0.4s; 81% likely beneficial), worst time (6.9±0.5s vs 7.1±0.5s; 78% likely beneficial) and total time (39.3±2.5s vs 40.4±2.5s; 81% likely beneficial) in the first repeated sprint ability set and for worst time (7.2±0.6s vs 7.5±0.6s; 57% possible beneficial) in the second repeated sprint ability set. Further, was found substantial change for total time for both repeated sprint ability tests (80.8±5.7s vs 83.4±5.6s; 52% possible beneficial). To conclude, four weeks of β-alanine supplementation had a likely beneficial effect in the first set of repeated sprint ability tests and a possible beneficial effect for worst time in the second set performed in a specific protocol in water polo players.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

et al. 2016

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“…Several original and review articles have described the positive effects of long-term beta-alanine supplementation on muscle performance [92][93][94][95][96], and chronic beta-alanine supplementation is a popular ergogenic strategy. It should be noted that a substantial decrease in the HIS content (~30%) in muscles and plasma after beta-alanine supplementation has been reported [89].…”

Section: Effects On Muscle Performance and Fatiguementioning

confidence: 99%

Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement

2020

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L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the histaminergic system. Several HIS-rich proteins (e.g., haemoproteins, HIS-rich glycoproteins, histatins, HIS-rich calcium-binding protein, and filaggrin), HIS-containing dipeptides (particularly carnosine), and methyl- and sulphur-containing derivatives of HIS (3-methylhistidine, 1-methylhistidine, and ergothioneine) have specific functions. The unique chemical properties and physiological functions are the basis of the theoretical rationale to suggest HIS supplementation in a wide range of conditions. Several decades of experience have confirmed the effectiveness of HIS as a component of solutions used for organ preservation and myocardial protection in cardiac surgery. Further studies are needed to elucidate the effects of HIS supplementation on neurological disorders, atopic dermatitis, metabolic syndrome, diabetes, uraemic anaemia, ulcers, inflammatory bowel diseases, malignancies, and muscle performance during strenuous exercise. Signs of toxicity, mutagenic activity, and allergic reactions or peptic ulcers have not been reported, although HIS is a histamine precursor. Of concern should be findings of hepatic enlargement and increases in ammonia and glutamine and of decrease in branched-chain amino acids (valine, leucine, and isoleucine) in blood plasma indicating that HIS supplementation is inappropriate in patients with liver disease.

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“…Numerous research has since demonstrated that βA supplementation (1.6–6.4 g·day − 1 for ≥28 days) augments the naturally occurring histidine dipeptide, carnosine ( β-alanyl-L-histidine ) within human muscle tissue [2–5]. As carnosine acts as a physico-chemical buffering agent (with an imidazole ring pK a of 6.83, and relative similarity to intracellular pH (6.5) [6–8]), βA supplementation was recently reported as producing small, yet significant performance improvements (effect size: 0.210; 95% CI: 0.057, 0.362) across a range of short (60–240 s) duration events [9] including cycling sprint performance [10], judo bouts [11], 800 m sprinting [12] and 1000 m rowing splits [13] in club-level through to well training men.…”

Section: Introductionmentioning

confidence: 99%

The effect of two β-alanine dosing strategies on 30-minute rowing performance: a randomized, controlled trial

Beasley

Smith

António

et al. 2018

Journal of the International Society of Sports Nutrition

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Backgroundβ-alanine (βA) supplementation has been shown to increase intramuscular carnosine content and subsequent high-intensity performance in events lasting < 4 minutes (min), which may be dependent on total, as opposed to daily, dose. The ergogenic effect of βA has also been demonstrated for 2000-m rowing performance prompting interest in whether βA may be beneficial for sustained aerobic exercise. This study therefore investigated the effect of two βA dosing strategies on 30-min rowing and subsequent sprint performance.MethodsFollowing University Ethics approval, twenty-seven healthy, male rowers (age: 24 ± 2 years; body-height: 1.81 ± 0.02 m; body-mass: 82.3 ± 2.5 kg; body-fat: 14.2 ± 1.0%) were randomised in a double-blind manner to 4 weeks of: i) βA (2.4 g·d− 1, βA1); ii) matched total βA (4.8 g on alternate days, βA2); or iii) cornflour placebo (2.4 g·d− 1, PL). Participants completed a laboratory 30-min rowing time-trial, followed by 3x30-seconds (s) maximal sprint efforts at days 0, 14 and 28 (T1-T3). Total distance (m), average power (W), relative average power (W·kg− 1), cardio-respiratory measures and perceived exertion were assessed for each 10-min split. Blood lactate ([La-]b mmol·L− 1) was monitored pre-post time-trial and following maximal sprint efforts. A 3-way repeated measures ANOVA was employed for main analyses, with Bonferonni post-hoc assessment (P ≤ 0.05).ResultsTotal 30-min time-trial distance significantly increased from T1-T3 within βA1 only (7397 ± 195 m to 7580 ± 171 m, P = 0.002, ƞp2 = 0.196), including absolute average power (194.8 ± 18.3 W to 204.2 ± 15.5 W, P = 0.04, ƞp2 = 0.115) and relative average power output (2.28 ± 0.15 W·kg− 1 to 2.41 ± 0.12 W·kg− 1, P = 0.031, ƞp2 = 0.122). These findings were potentially explained by within-group significance for the same variables for the first 10 min split (P ≤ 0.01), and for distance covered (P = 0.01) in the second 10-min split. However, no condition x time interactions were observed. No significant effects were found for sprint variables (P > 0.05) with comparable values at T3 for mean distance (βA1: 163.9 ± 3.8 m; βA2: 161.2 ± 3.5 m; PL: 162.7 ± 3.6 m), average power (βA1: 352.7 ± 14.5 W; βA2: 342.2 ± 13.5 W; PL: 348.2 ± 13.9 W) and lactate (βA1: 10.0 ± 0.9 mmol·L− 1; βA2: 9.2 ± 1.1 mmol·L− 1; PL: 8.7 ± 0.9 mmol·L− 1).ConclusionsWhilst daily βA may confer individual benefits, these results demonstrate limited impact of βA (irrespective of dosing strategy) on 30-min rowing or subsequent sprint performance. Further investigation of βA dosage > 2.4 g·d− 1 and/or chronic intervention periods (> 4–8 weeks) may be warranted based on within-group observations.

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Beta-alanine supplementation enhances judo-related performance in highly-trained athletes

Abstract: In conclusion, 4 weeks of beta-alanine supplementation effectively enhance judo-related performance in highly-trained athletes.

Cited by 50 publications

References 31 publications

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

Effects of Four Weeks of β-Alanine Supplementation on Repeated Sprint Ability in Water Polo Players

Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement

The effect of two β-alanine dosing strategies on 30-minute rowing performance: a randomized, controlled trial

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