beta-Lactam resistance of motile Aeromonas isolates from clinical and environmental sources

Morita, Koji; Watanabe, Noboru; Kurata, Satoru; Kanamori, Masato

doi:10.1128/aac.38.2.353

Cited by 31 publications

(19 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The large spectra of resistance to β-lactam antibiotics, the resistance to imipenem (a drug highly stable to serine-β-lactamases), as well as the inefficiency of clavulanic acid and sulbactam to inhibit Aeromonas β-lactamases, corroborate previous results indicating the chromosomally mediated production of metallo-β-lactamases by these bacteria (21,25). Furthermore, beyond the penicillins and first generation cephalosporins, some isolates (18.5%) showed resistance to several new extended-spectrum cephalosporins, and one isolate of A. hydrophila exhibited resistance to aztreonam and all the penicillins and cephalosponins.…”

Section: Resultssupporting

confidence: 84%

Aeromonas associated diarrhoeal disease in south Brazil: prevalence, virulence factors and antimicrobial resistance

Guerra¹,

Fadanelli²,

Figueiró³

et al. 2007

Braz. J. Microbiol.

View full text Add to dashboard Cite

Aeromonas were isolated from 27 (6.6%) of 408 patients admitted with acute gastroenteritis in two hospitals at Rio Grande do Sul, Brazil. Isolates were classified as A. hydrophila (51.8%), A. caviae (40.8%), and A. veronii biotype sobria (7.4%). The highest prevalence of Aeromonas associated infections occurred in lactants and children. Virulence genes (aerA -aerolysin/hemolysin, ahpA -serine-protease, satAglycerophospholipid-cholesterol acyltransferase, lipA -lipase, and ahyB -elastase) and virulence factors (hemolytic, proteolitic, lipolitic activities, and biofilm formation) were identified in most A. hydrophila and A. veronii biotype sobria isolates, with lower frequencies on A. caviae. All Aeromonas isolates were resistant to ampicillin, ticarcillin/clavulanic acid, cephalotin, and cephazolin, and most of them (>70%) exhibited resistance to imipenem, carbenicillin, amoxillin/sulbactan, and piperacillin. Multiple-resistance, more than four antibiotics, was evidenced in 29.6% of the isolates. The most efficient antibiotics were the quinolones (ciprofloxacin and norfloxacin), and the aminoglycosides (amikacin and netilmicin).

show abstract

Section: Resultssupporting

confidence: 84%

Aeromonas associated diarrhoeal disease in south Brazil: prevalence, virulence factors and antimicrobial resistance

Guerra¹,

Fadanelli²,

Figueiró³

et al. 2007

Braz. J. Microbiol.

View full text Add to dashboard Cite

show abstract

“…Remarkably in this work, imipenem resistance was observed in three isolates of Aeromonas (1 A. aquariorum, 1 A. veronii and 1 A. jandaei). Other studies also reported the incidence of strains resistant to this antibiotic [24,25]. Resistance to imipenem in non clinical strains supposed not subjected to selective pressure by use of such drug is a worrying trait as this is a last-resort antimicrobial agent used in the clinical environment.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial Resistance Patterns of Aeromonas spp. Isolated from Ornamental Fish

Días¹,

Mota²,

Martínez‐Murcia³

et al. 2012

J Aquac Res Development

View full text Add to dashboard Cite

The potential risk of occurrence of new diseases associated with the trade of live animals is well known. However, little importance is still given to the problematic of the dissemination of resistance genes that pass along with the animal trade. In this study we aimed to isolate Aeromonas spp. strains from water and skin of ornamental fish and test their resistance to antibiotics. The samples were collected from a national ornamental fish importer, with the intent of obtaining a collection of Aeromonas strains. The identification of the strains was made by gyrB and rpoD gene sequencing. A total of 288 strains grouped in seven different species -Aeromonas veronii, Aeromonas media, Aeromonas jandaei, Aeromonas hydrophila, Aeromonas caviae, Aeromonas culicicola, Aeromonas aquariorum, were isolated. The susceptibility profile was determined for 28 antibiotics commonly used. All the strains presented multi-resistance to the tested antibiotics. The antibiotic susceptibility profile to tetracycline, ticarcillin, carbenicillin, ampicillin and erythromycin revealed resistance levels of more than 80%. Few strains resistant to aztreonam and imipenem were identified. On the other hand, all were sensitive to cefotaxime and cefepime. The results show that these Aeromonas spp. strains are potentially reservoirs of antibiotic resistance genes.

show abstract

“…However, the results obtained using commercial kits and disc diffusion technique, especially the susceptibility tests to beta lactam antibiotics shoud be verified by agar dilution technique (Schadow et al 1993;Morita et al 1994). …”

Section: Discussionmentioning

confidence: 99%

Prevalence and Antibiotic Resistance of Motile Aeromonas in Dogs

Ceylan¹,

Berktaş²,

Körkoca³

et al. 2003

Acta Vet. Brno

View full text Add to dashboard Cite

The present study was carried out to assess the prevalence of motile Aeromonas sp. in the faeces of healthy dogs and to evaluate its susceptibility to some anti-microbial agents. Rectal swabs from 55 domestic dogs were examined for Aeromonas species using alkaline peptone water (pH 8.4) as the enrichment medium and Aeromonas Selective Agar containing 5 mg/l ampicillin as the plating medium. Identification and antibiotic resistance of motile Aeromonas strains was performed using Gram Negative Breakpoint ID panel. After examining these samples, aeromonads were isolated from three (5.45%) dogs. Of those, one was A. sobria, and two were A. caviae. While all isolated strains were sensitive to amikacin, cefoperazone, cefotaxime, cefotetan, ceftazidime, ceftriaxone, cefuroxime, ciprofloxacin, gentamicin, imipenem, piperacillin, tetracycline, ticarcillin, ticarcillin/clavulanate, tobramycin, and trimethoprim/sulfamethoxazole, they were resistant to ampicillin, and ampicillin/sulbactam. In addition, a strain of A. caviae was also resistant to aztreonam.As a result, in the present study, information about the prevalence of Aeromonas in dogs, susceptibility to antibiotics of these microorganisms and its importance for both animal and public health were discussed.

show abstract

beta-Lactam resistance of motile Aeromonas isolates from clinical and environmental sources

Cited by 31 publications

References 14 publications

Aeromonas associated diarrhoeal disease in south Brazil: prevalence, virulence factors and antimicrobial resistance

Aeromonas associated diarrhoeal disease in south Brazil: prevalence, virulence factors and antimicrobial resistance

Antimicrobial Resistance Patterns of Aeromonas spp. Isolated from Ornamental Fish

Prevalence and Antibiotic Resistance of Motile Aeromonas in Dogs

Contact Info

Product

Resources

About