Better clinical outcome for autologous fat transplant combined with silicone gel prosthesis for breast augmentation: Evidence from meta-analysis

Hoon, S.Y.; Cui, Chun Xiao; Cao, Dejun; Hong, Zhang Ru

doi:10.1016/j.asjsur.2019.03.003

Cited by 6 publications

(5 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On a PubMed search, we identified 12 meta-analyses published evaluating AFG in breast cancer patients that underwent breast reconstruction [ 20 , 46 – 56 ]. 4 of those evaluated complications associated with the procedure [ 48 , 52 , 53 , 56 ], 2 evaluated aesthetical outcomes [ 34 , 51 ], two evaluated different fat grafting techniques [ 54 , 55 ] and only four evaluated local recurrence as an oncological outcome [ 46 , 47 , 49 , 50 ]. None of these four that evaluated oncological outcomes had a formal evaluation of the quality of the studies, and none of them evaluated OS.…”

Section: Discussionmentioning

confidence: 99%

The oncological safety of autologous fat grafting: a systematic review and meta-analysis

et al. 2022

View full text Add to dashboard Cite

Objective To present a systematic review of the literature and a meta-analysis evaluating the oncological safety of autologous fat grafting (AFG). Summary background data: AFG for breast reconstruction presents difficulties during follow-up radiological exams, and the oncological potential of grafted fat is uncertain. Previous studies confirmed that the fatty tissue could be transferred under a good condition suitable would not interfere with mammographic follow-up, although the issue of oncological safety remains. Methods We reviewed the literature published until 01/18/2021. The outcomes were overall survival (OS), disease-free survival (DFS), and local recurrence (LR). We included studies that evaluated women with breast cancer who undergone surgery followed by reconstruction with AFG. We synthesized data using the inverse variance method on the log-HR (log of the hazard ratio) scale for time-to-event outcomes using RevMan. We assessed heterogeneity using the Chi2 and I2 statistics. Results Fifteen studies evaluating 8541 participants were included. The hazard ratios (HR) could be extracted from four studies, and there was no difference in OS between the AFG group and control (HR 0.9, 95% CI 0.53 to 1.54, p = 0.71, I2 = 58%, moderate certainty evidence), and publication bias was not detected. The HR for DFS could be extracted from six studies, and there was no difference between the AFG group and control (HR 1.01, 95% CI 0.73 to 1.38, p = 0.96, I2 = 0%, moderate certainty evidence). The HR for LR could be extracted from ten studies, and there was no difference between the AFG group and control (HR 0.86, 95% CI 0.66 to 1.12, p = 0.43, I2 = 1%, moderate certainty evidence). Conclusion According to the current evidence, AFG is a safe technique of breast reconstruction for patients that have undergone BC surgery and did not affect OS, DFS, or LR.

show abstract

Section: Discussionmentioning

confidence: 99%

The oncological safety of autologous fat grafting: a systematic review and meta-analysis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Lipomodelling alone can be used for cosmetic volume enhancement 24 or it can be used following primary augmentation in either the immediate 25 or delayed setting in order to make implants less visible 26 .…”

Section: Aesthetic Breast Surgerymentioning

confidence: 99%

UK Guidelines for Lipomodelling of the Breast on behalf of Plastic, Reconstructive and Aesthetic Surgery and Association of Breast Surgery Expert Advisory Group

Skillman

McManus

Bhaskar

et al. 2022

Journal of Plastic, Reconstructive & Aesthetic Surgery

View full text Add to dashboard Cite

“…[29][30][31][32][33] Furthermore, the use of autologous fat grafting can aid in blending in contour irregularities and may even soften a firm, unnatural feeling skin envelope. [34][35][36][37][38] Increasing awareness of techniques to optimize a patient's aesthetic outcome to the public may prompt those who were previously unsure of their willingness to receive implants to seek consultation. As concerns regarding surgical scars, appearance, and feel of the breast were particularly present in younger respondents, social media platforms such as Instagram may be potential avenues to reach this population and disseminate such information.…”

Section: E Educating Prospective Patients On Costs and Outcomesmentioning

confidence: 99%

Identifying Public Perceptions, Attitudes, and Concerns About Breast Implants and Their Complications: A National Survey with Implications for Practice

Lee

Khavanin

Xun

et al. 2022

Plastic &Amp; Reconstructive Surgery

View full text Add to dashboard Cite

esthetic and reconstructive implant-based breast operations are among the most common plastic surgery procedures. Breast augmentation has ranked as the top cosmetic procedure since 2006, and a combined total of more than 380,000 implant-based procedures are performed annually in the United States. 1,2 Despite the continuous popularity of these procedures, short-and long-term complications such as capsular contracture and implant migration are not uncommon. [3][4][5] Approximately 25% to 36% of women experience complications related to implant-based procedures that require revision

show abstract

Better clinical outcome for autologous fat transplant combined with silicone gel prosthesis for breast augmentation: Evidence from meta-analysis

Cited by 6 publications

References 37 publications

The oncological safety of autologous fat grafting: a systematic review and meta-analysis

The oncological safety of autologous fat grafting: a systematic review and meta-analysis

UK Guidelines for Lipomodelling of the Breast on behalf of Plastic, Reconstructive and Aesthetic Surgery and Association of Breast Surgery Expert Advisory Group

Identifying Public Perceptions, Attitudes, and Concerns About Breast Implants and Their Complications: A National Survey with Implications for Practice

Contact Info

Product

Resources

About