Abstract. Understanding past and present hydro-system feedbacks to global ocean-atmospheric interactions represents one of the main challenges to preventing droughts, extreme events and related human catastrophes in the face of global warming, especially in arid and semiarid environments. In eastern Africa, the El Niño-Southern Oscillation (ENSO) was identified as one of the primary drivers of precipitation variability affecting water availability. However, the northern East African Rift System (EARS) still suffers from ENSO climate teleconnection and the underrepresentation of predictive models because of the scarcity of local-to-regional historical or palaeo-data. In this paper, we provide a 50-year seasonal flood/drought chronicle of the Awash River catchment from the study of laminated sediment from Gemeri and Afambo lakes (Central Afar region, Ethiopia), with the aim of reconstructing the magnitude of regional hydro-climatic events. Pluri-centimetric micro-laminated lithogenic facies alternating with pluri-millimetric carbonate-enriched facies are investigated in both lakes. We couple dating methods including radiocarbon, short-lived radionuclides, palaeomagnetic field variations and varve counting on both lake deposits to build a high-resolution age model and to discuss the regional hydro-sedimentary dynamics of the Awash River over the last ~700 years, with a focus on the last fifty years. Using a multiproxy approach, we observe that following a multi-centennial enhanced hydrological period, the two lakes experienced a gradual decrease in river load inflow since 1979 CE, attaining extreme drought and high evaporative conditions between 1991 and 1997 CE. In 2014, the construction of a dam and the improvement of agricultural hydraulic management in the lower Awash River plain impacted the erodibility of local soils and the hydro-sedimentary balance of the lake basins, as evidenced by a disproportionate sediment accumulation rate. Comparison of our quantitative reconstruction with i) lake water surface evolution expressed in Km2, ii) the interannual Awash River flow rates expressed in mm/yr, and iii) the El Niño 3.4 model highlights the intermittent connections between ENSO SST anomalies, regional droughts and hydrological conditions in the northern EARS.