Bibliography

MAUPIN, BERNARD

doi:10.1016/b978-1-4832-8297-8.50020-2

Blood Platelets in Man and Animals 1969

DOI: 10.1016/b978-1-4832-8297-8.50020-2

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BERNARD MAUPIN

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Cited by 4 publications

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Insignificance of Gluconeogenesis in Human Blood Platelets

Schrijver

Koster

Hülsmann

1975

Eur J Clin Investigation

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Human blood platelets contain no detectable activity of the enzymes fructose diphosphatase (EC 3.1.3.11), phospho-enolpyruvate carboxykinase (EC 4.1.1.32) and pyruvate carboxylase (EC 6.4.1.1.). Glucose-6-phosphatase (EC 3.1.3.9) activity is very low. Phosphofructokinase present in human blood platelets, catalyzes a reaction which can be stimulated by AMP in a platelet homogenate, due to the presence of endogenous ADP and myokinase. These enzymes are responsible for the formation of fructose-6-phosphate from fructose-1, 6-diphosphate. Pyruvate kinase (EC 2.7.1.40) in human blood platelets belongs to the M-type, which is not inhibited by ATP, at least not under the conditions applied. The results obtained indicate that gluconeogenesis in human blood platelets is not present in the way which has been established for liver and kidney.

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Insignificance of Gluconeogenesis in Human Blood Platelets

Schrijver

Koster

Hülsmann

1975

Eur J Clin Investigation

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Prophylactic Platelet Transfusions in Children with Acute Leukemia: A Dose Response Study

1973

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A study of the value of small doses of platelets given prophylactically in thrombocytopenic patients was carried out. Transfusions of two dose levels of platelets were compared: 0.03 units/1b (low dose) and 0.06 units/lb of body weight (high dose). The incidence of bleeding in nontransfused patients seen here prior to this study was also determined. The difference in incidences of bleeding among patients transfused with low or high dose was not significant. The differences between the transfused and nontransfused patients were highly significant.

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Cyclic Fluctuations in Platelet Count, Megakaryocyte Maturation and Thrombopoietin Activity in Cyanotic Congenital Heart Disease

Goldschmidt

Fono

1972

Acta Paediatrica

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Bibliography

Cited by 4 publications

References 2,455 publications

Insignificance of Gluconeogenesis in Human Blood Platelets

Insignificance of Gluconeogenesis in Human Blood Platelets

Prophylactic Platelet Transfusions in Children with Acute Leukemia: A Dose Response Study

Cyclic Fluctuations in Platelet Count, Megakaryocyte Maturation and Thrombopoietin Activity in Cyanotic Congenital Heart Disease

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