With the continuous development of the Internet of Things (IoT) technology, the industry’s awareness of the security of the IoT is also increasing, and the adoption of quantum communication technology can significantly improve the communication security of various devices in the IoT. This paper proposes a scheme of controlled remote quantum state preparation and quantum teleportation based on multiple communication parties, and a nine-qubit entanglement channel is used to achieve secure communication of multiple devices in the IoT. The channel preparation, measurement operation, and unitary operation of the scheme were successfully simulated on the IBM Quantum platform, and the entanglement degree and reliability of the channel were verified through 8192 shots. The scheme’s application in the IoT was analyzed, and the steps and examples of the scheme in the secure communication of multiple devices in the IoT are discussed. By simulating two different attack modes, the effect of the attack on the communication scheme in the IoT was deduced, and the scheme’s high security and anti-interference ability was analyzed. Compared with other schemes from the two aspects of principle and transmission efficiency, it is highlighted that the advantages of the proposed scheme are that it overcomes the single fixed one-way or two-way transmission protocol form of quantum teleportation in the past and can realize quantum communication with multiple devices, ensuring both security and transmission efficiency.