Bilateral acute depigmentation of iris: A report of two cases

Ersöz, Mehmet Giray; Doğan, Beysim; Nacaroğlu, Şenay Aşık; Ayıntap, Emre; Adıyeke, Seda Karaca; Türe, Gamze

doi:10.5222/terh.2016.085

Cited by 3 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Since its initial characterization by Tukal-Tutkun et al, in 2005, fewer than 100 cases of both BADI and BAIT have been described worldwide: 51 in Turkey, 4 in the Netherlands, 4 in Belgium, 4 in Colombia, one in Spain, one in France and one in Brazil. 1 , 2 , 3 , 7 , 8 , 9 , 7 , 8 , 9 To our knowledge, there are no previous reports of BADI cases in the Middle East and Africa. Here, we present the first two cases of BADI in the region.…”

Section: Introductionmentioning

confidence: 79%

Bilateral acute depigmentation of the iris in two siblings simultaneously

Amin

Nabih²,

Khater

2018

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

PurposeTo report the first simultaneous onset of bilateral acute depigmentation of the iris (BADI) in two siblings.ObservationsTwo sisters presented with bilateral ocular pain, redness and light sensitivity. Examination revealed bilateral circulating pigment in the anterior chamber with pigment dusting on backs of the corneas, patchy iris depigmentation and heavy pigment deposition in the angle. Both patients had recently suffered from upper respiratory tract infections. Bilateral visual acuities were preserved and no transillumination defects were observed. The patients were diagnosed with BADI. Both cases were successfully controlled with topical corticosteroids and anti-glaucoma drops as well as topical glanciclovir gel.Conclusions and ImportanceTo date, there had been no published reports of BADI in the Middle East and Africa. This is the first observation of this entity in these regions. Moreover it is the first occurrence of BADI in two immediate siblings simultaneously. We also report the rare asymmetrical presentation with BADI in one of our patients. These observations point to the possibility of genetic factors underlying BADI as well as an infectious cause behind the etiology.

show abstract

Section: Introductionmentioning

confidence: 79%

Bilateral acute depigmentation of the iris in two siblings simultaneously

Amin

Nabih²,

Khater

2018

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

show abstract

“…Therefore, iris transillumination defect and sphincter paralysis do not appear in BADI, and iris discoloration with granular appearance may be reversible. 2 , 7 Often overlooked in practice and treated like iridocyclitis, diagnosis of BADI can be easily made with consideration paid to the examination findings clinically. The first one of these is stromal depigmentation and granular appearance of iris without iris transillumination defect, the second one is that there are no inflammatory cells in the anterior chamber and corneal endothelium even in acute attacks, and the third one is that it always displays bilateral symmetrical involvement.…”

Section: Discussionmentioning

confidence: 99%

Bilateral acute depigmentation of iris: 3-year follow-up of a case

et al. 2018

View full text Add to dashboard Cite

Bilateral acute depigmentation of the iris (BADI) usually affecting young women, is a newly defined clinical diagnosis with bilateral symmetrical pigment loss of iris stroma without iris transillumination defect. Herein, we want to share the results of a 3-year-long follow-up of a 23-year old female patient with BADI. She was admitted to our clinic with a complaint of discoloration of both her brown irises. An ocular evaluation of the patient revealed symmetrical pigment deposition in trabecular meshwork. No iris transillumination defect, pupillary sphincter paralysis, keratic precipitates, and inflammatory reaction in anterior chamber were seen. The depigmented iris stroma became repigmented symmetrically after 3-year follow-up period. Although it is rare, BADI should be considered in the differential diagnosis of the diseases with bilateral iris depigmentation.

show abstract

“…При BAIT это осложнение возникает раньше и трудно поддается лечению, иногда вызывая истинную пост-BAIT глаукому, что в отдельных случаях может приводить к необходимости оперативного вмешательства [15,16]. Синдром BADI имеет более благоприятный прогноз с офтальмологической точки зрения, так как характер патологических изменений наносит переднему отрезку глаза меньший ущерб [17].…”

unclassified

Causes of Iris Depigmentation in Young and Middle Age. Clinical Example

et al. 2020

View full text Add to dashboard Cite

The spontaneous change of eyes’ color is a quite rare complain in ophthalmological clinical practice for young and middle-aged patients. We consulted the 18-year-old patient complained that a month ago she noticed a change of the iris’ color. It was symmetrical in both eyes, which had lightened and acquired a “spotty appearance”. Before the appearance of these complaints, the patient had eyes of a rich dark brown color. After a comprehensive examination, the bilateral acute iris depigmentation (BADI) was diagnosed. BADI is bilateral symmetrical iris depigmentation followed by focal or diffuse stromal atrophy and pigment dispersion in the anterior segment. It is more common for young and middle-aged women, and is often asymptomatic. BADI has bilateral symmetrical iris depigmentation followed by focal or diffuse stromal atrophy and pigment dispersion in the anterior eye segment of the eye, which may affect the trabecular network. A feature of this disease is the absence of transillumination, changes in the shape of the pupil, and an inflammatory reaction. In some cases, repigmentation may occur spontaneously during the next few years. Therefore, from a prognostic point this disease has a favorable prognosis. However, patients with BADI syndrome should undergo regular ophthalmological examinations, including measurement of intraocular pressure to exclude the development of secondary open-angle pigmented glaucoma, and use sunglasses when the sun is bright. BADI syndrome must be differentiated with the following diseases: Fuchs heterochromic iridocyclitis, viral iridocyclitis caused by HSV and CMV, pigment dispersion syndrome and pseudo exfoliative glaucoma, as well as bilateral acute iris transillumination (BAIT) syndrome to make a correct diagnosis and apply adequate treatment tactics.

show abstract

Bilateral acute depigmentation of iris: A report of two cases

Cited by 3 publications

References 14 publications

Bilateral acute depigmentation of the iris in two siblings simultaneously

Bilateral acute depigmentation of the iris in two siblings simultaneously

Bilateral acute depigmentation of iris: 3-year follow-up of a case

Causes of Iris Depigmentation in Young and Middle Age. Clinical Example

Contact Info

Product

Resources

About