Bilateral Cystosarcoma Phyllodes, Malignant Variant, with 14-Year Followup A Case Report

Reich, Theobald; Solomon, Cyril

doi:10.1097/00000658-195801000-00006

Cited by 19 publications

(8 citation statements)

References 4 publications

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“…Some authors feel that the lesion also can arise de novo from breast parenchyma (Dyer et al, 1966;Hafner et al, 1962;Treves, 1964). Trauma, lactation, pregnancy (Bader and Isaacson, 1961;Reich and Solomon, 1958) and increased estrogen activity (Gibbs, et al, 1968;Wulsin, 1960) occasionally have been implicated as factors stimulating tumor growth. Minkowitz et a1 .…”

Section: Etiologymentioning

confidence: 99%

“…The skeleton was involved in 28.3% of cases, the heart in 9.4% of cases, and the liver in 5.6% cases. No organ system is spared as metastatic lesions have been found in the stomach (Lester and Stout, 1954), pancreas (Lester and Stout, 1954), omentum (Reich and Solomon, 1958), larynx (Lester and Stout, 1954), kidney (Norris andTaylor, 1967), adrenal (McCullough andLynch, 1960), spleen (Norris and Taylor, 1967), cervical nodes (Norris and Taylor, 1967), para-aortic nodes (Norris and Taylor, 1967), mediastinum (White, 1940), subpleural extrapulmonary space (Steckler and Landman, 1950), pleura (Oberman, 1965), abdominal wall (Treves and Sunderland, 1951), gum (Treves and Sunderland, 1951), vulva (Treves and Sunderland, 1951), scalp (Treves and Sunderland, 1951), and even the sole of the foot (Treves and Sunderland, 1951).…”

Section: Metastasismentioning

confidence: 99%

“…In 1958, Reich and Solomon (Reich and Solomon, 1958) reported the first case of bilateral histologically malignant cystosarcoma phyllodes with metastasis. A subsequent similar case has been reported by Notley and Griffiths (Notley and Griffiths, 1965).…”

Section: Introductionmentioning

confidence: 99%

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Metastatic cystosarcoma phyllodes: A case report and review of the literature

Kessinger¹,

Foley²,

Lemon³

et al. 1972

Journal of Surgical Oncology

149

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The breast tumor cystosarcoma phyllodes probably does not Rpresent an entity, but rather a spectrum of disease including a benign form, a histologically malignant form, and a metastatic form. In an attempt to better understand the metastatic variant, all 66 cases which could be found in the english literature and an additional case from this institution were reviewed.The tumor often arises from a fibroadenoma, but its etiology is uncertain. Factors that determine the benignity or malignancy of the tumor are unknown, but a lower fertility rate in patients with metastases warrants interest.Incidence is low; cystosarcoma makes up about 0.5% of alI breast tumors and only 3-12% of these are metastatic.The tumor presents as a breast mass, often of large size, but there is no clinical feature peculiar to the metastatic variant.Gross and microscopic pathologic findings cannot accurately forecast the metastatic potential of the tumor, but are of more predictive value than the clinical presentation. The clinical course is the only sure means of determining metastatic potential at present.

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Section: Etiologymentioning

confidence: 99%

Section: Metastasismentioning

confidence: 99%

See 1 more Smart Citation

Metastatic cystosarcoma phyllodes: A case report and review of the literature

Kessinger¹,

Foley²,

Lemon³

et al. 1972

Journal of Surgical Oncology

149

View full text Add to dashboard Cite

show abstract

“…4 of their benign cases were bilateral [16]. The first report of malignant cystosarcoma phyllodes bilaterally was by Reich and Solomon in 1958 in which both breasts became involved in association with pregnancy [24]. Bader and Isaacson in 1961 reported another case with the apparent stimulus of pregnancy [2] and in 1965 Motley and G riffiths reported the third case of bilateral malignant cystosar coma phyllodes [17].…”

Section: Literature Reviewmentioning

confidence: 99%

“…A benign form which may recur after surgery but does not metastasize has been reported [3,15]. Metastatic tumor has appeared and eventually caused death in patients as long as 14 years after the original tumor was treated [24]. Axillary lymph node metastasis has been reported only four times.…”

Section: Literature Reviewmentioning

confidence: 99%